Rabbit anti-WDR5 Antibody, Affinity Purified

The epitope recognized by PLA0256 maps to a region between residue 50 and 100 of human WD repeat domain 5 using the numbering given in entry NP_060058.1 (GeneID 11091).

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

WD-repeat domain 5 (WDR5) is a member of the WD repeat family. The WD repeat is defined by four or more repeating units of a conserved core of approximately 40 amino acids ending with tryptophan-aspartic acid (WD). WD repeats may serve as sites of protein-protein interaction for adaptor proteins and facilitate multiprotein complex formation. WDR5 contains 7 WD repeats and is a core subunit of the human MLL and SET1 histone H3 lys4 methyltransferase complexes. WDR5 functions in facilitating the assembly of MLL and SET1 chromatin-modifiying complexes.

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