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安全信息

PLA0205

Sigma-Aldrich

兔抗 CREB 抗体,亲和纯化

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别名:
5′-monophosphate response element-binding protein CREB, CREB, CREB-1, active transcription factor CREB, cAMP-response element-binding protein-1, cAMP-responsive element-binding protein 1, cyclic adenosine 3′, transactivator protein
UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

抗体形式

affinity purified immunoglobulin

抗体产品类型

primary antibodies

等级

Powered by Bethyl Laboratories, Inc.

种属反应性

mouse, human

技术

immunohistochemistry: 1:100- 1:1,000
immunoprecipitation (IP): 2-5 μg/mg
western blot: 1:2,000- 1:10,000

登记号

NP_604391.1

运输

wet ice

储存温度

2-8°C

靶向翻译后修饰

unmodified

基因信息

rabbit ... CREB(1385)

免疫原

The epitope recognized by PLA0205 maps to a region between residue 250 and 300 of human cAMP responsive element binding protein 1 using the numbering given in entry NP_604391.1 (GeneID 1385).

外形

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

其他说明

CREB (cyclic AMP response element-binding protein) is a ubiquitously expressed transcription factor that binds cAMP response elements to regulate gene transcription for various cellular responses such as glucose homeostasis, growth-factor dependent survival, and proliferation. CREB is also implicated to play a role in memory and mood.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品
含少量动物源组分生物产品

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Celine I Maeder et al.
Cell, 174(6), 1436-1449 (2018-08-28)
Synaptic vesicle and active zone proteins are required for synaptogenesis. The molecular mechanisms for coordinated synthesis of these proteins are not understood. Using forward genetic screens, we identified the conserved THO nuclear export complex (THOC) as an important regulator of

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