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Merck
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安全信息

PLA0181

Sigma-Aldrich

Rabbit anti-PSF/SFPQ Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

别名:

100 kDa DNA-pairing protein, 100 kDa subunit, DNA-binding p52/p100 complex, POMP100, PPP1R140, PSF, PTB-associated splicing factor, PTB-associated-splicing factor, hPOMp100, polypyrimidine tract binding protein associated, polypyrimidine tract-binding protein-associated splicing factor, polypyrimidine tract-binding protein-associated-splicing factor, protein phosphatase 1, regulatory subunit 140, splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated), splicing factor proline/glutamine rich (polypyrimidine tract-binding protein-associated), splicing factor proline/glutamine-rich

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

100

抗体形式

affinity purified immunoglobulin

抗体产品类型

primary antibodies

等级

Powered by Bethyl Laboratories, Inc.

种属反应性

human, mouse

技术

immunohistochemistry: 1:100- 1:500
immunoprecipitation (IP): 2-5 μg/mg
western blot: 1:2,000- 1:10,000

登记号

NP_005057.1

运输

wet ice

储存温度

2-8°C

靶向翻译后修饰

unmodified

基因信息

rabbit ... PSF/SFPQ(6421)

免疫原

The epitope recognized by PLA0181 maps to a region between residue 225 and 275 of human Polypyrimidine tract-binding protein-associated-splicing factor (Splicing factor, proline- and glutamine-rich) using the numbering given in entry NP_005057.1 (GeneID 6421).

外形

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

其他说明

PSF/SFPQ is a multifunctional protein know to participate in a variety of nuclear processes and may function to link transcription and pre-mRNA processing. PSF/SFPQ bears an RNA recognition motif (RRM) further indicating its role in post-transcriptional processes. PSF has been shown to associate with p54nrb/NonO to modulate androgen receptor-mediated transcription. Additionally, it has recently been show to associate with XRN2 and p54nrb/NonO to facilitate pre-mRNA 3′ processing and transcription termination.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

含少量动物源组分生物产品
常规特殊物品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
1

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Claudia Fierro et al.
Nature communications, 14(1), 3795-3795 (2023-06-27)
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Bin Zhou et al.
mBio, 10(4) (2019-08-01)
Endogenous retroviruses (ERVs) are transposable elements that cause host genome instability and usually play deleterious roles in disease such as tumorigenesis. Recent advances also suggest that this "enemy within" may encode a viral mimic to induce antiviral immune responses through

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