PLA0179
Rabbit anti-NBS1 Antibody, Affinity Purified
Powered by Bethyl Laboratories, Inc.
别名:
AT-V1, AT-V2, ATV, NBS, NBS1, Nijmegen breakage syndrome 1 (nibrin), Nijmegen breakage syndrome protein 1, P95, cell cycle regulatory protein p95, p95 protein of the MRE11/RAD50 complex
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所有图片(3)
About This Item
UNSPSC代码:
12352203
NACRES:
NA.41
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生物来源
rabbit
质量水平
抗体形式
affinity purified immunoglobulin
抗体产品类型
primary antibodies
等级
Powered by Bethyl Laboratories, Inc.
种属反应性
human
技术
immunohistochemistry: 1:100- 1:500
immunoprecipitation (IP): 2- 5 μg/mg
western blot: 1:2,000- 1:10,000
登记号
NP_002476.2
运输
wet ice
储存温度
2-8°C
基因信息
rabbit ... NBS1(4683)
免疫原
The epitope recognized by PLA0179 maps to a region between residue 704 and 754 of human Nibrin using the numbering given in entry NP_002476.2 (GeneID 4683).
外形
Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide
其他说明
Mutations in NBS1 (Nijmegen Breakage Syndrome 1), also known as nibrin, are associated with the autosomal recessive syndrome, Nijmegen breakage syndrome, characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. At the cellular level, NBS1 is part of the MRE11/RAD50 double-strand break repair complex that is critical to the DNA damage response, DNA recombination, telomere integrity, and cell cycle checkpoint control.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
含少量动物源组分生物产品
Jérémie Fages et al.
PLoS genetics, 16(6), e1008511-e1008511 (2020-07-01)
Ribosomal DNA (rDNA) is the most transcribed genomic region and contains hundreds of tandem repeats. Maintaining these rDNA repeats as well as the level of rDNA transcription is essential for cellular homeostasis. DNA damages generated in rDNA need to be
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