Rabbit anti-Filamin A Antibody, Affinity Purified

The epitope recognized by PLA0168 maps to a region between residue 2597 and 2647 of human Filamin A using the numbering given in entry NP_001447.1 (GeneID 2316).

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Filamin A is an actin-binding protein that crosslinks and promotes orthogonal branching of actin filaments and also functions to anchor transmembrane proteins and intracellular signaling proteins to the actin cytoskeleton. As a scaffolding protein, filamin A is able act as a link between cell membrane receptors and intracellular signaling proteins. Defects in Filamin A are associated with multiple human diseases characterized by abnormalities in bone and neurological development.

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