Rabbit anti-PPP5C Antibody, Affinity Purified

The epitope recognized by PLA0156 maps to a region between residue 1 and 50 of human Protein Phosphatase 5, Catalytic Subunit using the numbering given in entry NP_006238.1 (GeneID 5536).

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

PPP5C is the protein phosphatase 5 catalytic unit that is a member of the large PPP family of serine/threonine protein phosphatases. PPP5C plays a role in mediating stress-activated signaling pathways and the DNA damage response. Unlike PP1, PP2A, and PPP4, which function as dimeric or trimeric enzymes, PPP5 functions as a monomer. PPP5 exists as a regulatory N-terminal tetratricopeptide repeat (TPR) domain fused to a C-terminal phosphatase catalytic domain. PPP5C has been demonstrated to associate with and regulate ATM and DNA-PK.

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