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Merck
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主要文件

安全信息

PLA0060

Sigma-Aldrich

Rabbit anti-MCM2 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

别名:

BM28, CCNL1, CDCL1, D3S3194, DFNA70, KIAA0030, MCM2 minichromosome maintenance deficient 2, cdc19, cell devision cycle-like 1, cyclin-like 1, minichromosome maintenance deficient (S. cerevisiae) 2 (mitotin), minichromosome maintenance deficient 2 (mitotin), minichromosome maintenance protein 2 homolog, mitotin, mitotin (S. cerevisiae), nuclear protein BM28

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

100

抗体形式

affinity purified immunoglobulin

抗体产品类型

primary antibodies

等级

Powered by Bethyl Laboratories, Inc.

种属反应性

human, mouse

技术

immunohistochemistry: 1:2,000-1:10,000
immunoprecipitation (IP): 2- 5 μg/mg
western blot: 1:1,000- 1:10,000

登记号

NP_0045117.2

UniProt登记号

P49736

运输

wet ice

储存温度

2-8°C

靶向翻译后修饰

unmodified

基因信息

rabbit ... MCM2(4171)

相关类别

免疫原

The epitope recognized by PLA0060 maps to a region between residues 1 and 50 of human human minichromosomal maintenance deficient 2 using the numbering given in entry NP_0045117.2 (GeneID 4171).

外形

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

其他说明

The MCM (Mini-Chromosome Maintenance) complex is a key component of the pre-replication complex involved in replication licensing which restricts DNA replication to only once per cell cycle. The MCM complex is a heterohexamer of MCM2, MCM3, MCM4, MCM5, MCM6, and MCM7. MCM2 interacts with the core MCM complex (MCM4, 6, and 7) to regulate its helicase activity.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

12 - Non Combustible Liquids

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
2

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Maïté Leturcq et al.
Cellular and molecular life sciences : CMLS, 75(23), 4321-4339 (2018-08-03)
O-GlcNAcylation of proteins is governed by O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA). The homeostasis of O-GlcNAc cycling is regulated during cell cycle progression and is essential for proper cellular division. We previously reported the O-GlcNAcylation of the minichromosome maintenance proteins

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