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Merck
CN

PHG0005

SAFC

BIS-TRIS丙烷

制药生产

别名:

1,3-双[三(羟甲基)甲氨基]丙烷

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About This Item

线性分子式:
CH2[CH2NHC(CH2OH)3]2
CAS号:
分子量:
282.33
Beilstein:
1786109
EC 号:
MDL编号:
UNSPSC代码:
12161705
NACRES:
NA.21

生物来源

synthetic

质量水平

表单

powder

技术

cell culture | mammalian: suitable

杂质

Endotoxin, microbial, and trace metals; tested

有效pH范围

6.3-9.5

pKa (25 °C)

(1) 6.8, (2) 9.0

mp

164-165 °C (lit.)

适用性

suitable for manufacturing use

异质活性

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

SMILES字符串

OCC(CO)(CO)NCCCNC(CO)(CO)CO

InChI

1S/C11H26N2O6/c14-4-10(5-15,6-16)12-2-1-3-13-11(7-17,8-18)9-19/h12-19H,1-9H2

InChI key

HHKZCCWKTZRCCL-UHFFFAOYSA-N

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一般描述

我们用于生物制药加工的SAFC®系列优质原料经过严格的质量控制流程,配合记录文件和技术专长帮助我们的客户达到M-Clarity 计划规定的要求

M-Clarity 计划

缓冲液质量是生物制药工艺成功的关键,因为缓冲液几乎在每一个生产步骤中都是必不可少的。

我们广泛的缓冲材料产品线经过妥善管控,可根据您的需求量身定制。从低风险应用的非 GMP 等级,到高风险应用的 IPEC-PQG GMP标准,我们的产品可满足您的所有制造需求。

应用

Bis Tris丙烷是一种独特的生物缓冲液,也可称为“通用型”缓冲液,因为它的缓冲范围很广。Bis Tris丙烷有两个pKa值,6.3和9.5,所以缓冲范围扩展到5.0-10.5,在生物体系中用途广泛。Bis Tris丙烷对培养细胞无毒,并具有高溶液澄清度。

一篇关于DNA聚合酶技术的综述因Bis Tris丙烷宽广的缓冲pH梯度而将其列为适合PCR的缓冲液。

法律信息

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

替代产品

产品编号
说明
价格

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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