P9764
聚脱氧腺苷酸•聚胸苷酸 钠盐
double-stranded homopolymer
别名:
Poly(dA) • Poly(dT)
SMILES string
[P](=O)(OCC4OC(CC4O)N5C=C(C(=O)NC5=O)C)(O)O.[P](=O)(OCC1OC(CC1O)[n]2c3ncnc(c3nc2)N)(O)O
InChI
1S/C10H14N5O6P.C10H15N2O8P/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(21-7)2-20-22(17,18)19;1-5-3-12(10(15)11-9(5)14)8-2-6(13)7(20-8)4-19-21(16,17)18/h3-7,16H,1-2H2,(H2,11,12,13)(H2,17,18,19);3,6-8,13H,2,4H2,1H3,(H,11,14,15)(H2,16,17,18)
InChI key
KKVQVIFXABFJCS-UHFFFAOYSA-N
biological source
synthetic (organic)
form
powder
storage temp.
−20°C
Quality Level
Application
聚脱氧腺苷酸•聚胸苷酸（Poly(dA) • Poly(dT)）是一种双链均聚物，用作DNA结构动力学和药物相互作用构象研究的DNA模型。
Other Notes
双链均聚物
在1.0 ml 20 mM磷酸钠/100 mM NaCl、pH 7.0的溶液中，一单位酶可产生1.0的A260
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Yue Zhou et al.
BMC genomics, 5, 95-95 (2004-12-16)
DNA homopolymer tracts, poly(dA).poly(dT) and poly(dG).poly(dC), are the simplest of simple sequence repeats. Homopolymer tracts have been systematically examined in the coding, intron and flanking regions of a limited number of eukaryotes. As the number of DNA sequences publicly available
Hannah E J Polson et al.
Molecular and biochemical parasitology, 141(2), 179-189 (2005-04-27)
Expression of the Plasmodium falciparum calmodulin gene (pfcam) is developmentally regulated throughout the blood-stage cycle. The promoter lies within approximately 1 kb of intergenic sequence that separates the pfcam open reading frame (ORF) from an upstream inverted ORF encoding a
Dev P Arya
Accounts of chemical research, 44(2), 134-146 (2010-11-16)
A DNA duplex can be recognized sequence-specifically in the major groove by an oligodeoxynucleotide (ODN). The resulting structure is a DNA triple helix, or triplex. The scientific community has invested significant research capital in the study of DNA triplexes because
Taegi Park et al.
Biochimica et biophysica acta, 1726(3), 287-292 (2005-09-01)
The binding modes of the free-base meso-tetrakis(N-methylpyridinium-4-yl)porphyrin (TMPyP) complexed with [d(AT)n]2 oligonucleotides (where n=3-8, corresponding to 6 to 16 AT base pairs) were studied by circular dichroism (CD). When associated with the shortest oligonucleotide, ([d(AT)3]2), a bisignate CD spectrum was
Hongjuan Xi et al.
Biochemistry, 50(42), 9088-9113 (2011-08-26)
Recognition of nucleic acids is important for our understanding of nucleic acid structure as well as for our understanding of nucleic acid-protein interactions. In addition to the direct readout mechanisms of nucleic acids such as H-bonding, shape recognition of nucleic
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