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Merck
CN

P9763

Sigma-Aldrich

L-α-磷脂酰肌醇 4,5-二磷酸酯 钠盐 来源于牛大脑

≥98% (TLC)

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别名:
1,2-二酰基-sn-甘油-3-磷酸基-(1-D-myo-肌醇 4,5-二磷酸酯) 钠盐, PIP2, 三磷酸肌醇磷脂 钠盐
UNSPSC代码:
12352211

生物来源

bovine brain

检测方案

≥98% (TLC)

形式

powder

官能团

phospholipid

运输

dry ice

储存温度

−20°C

生化/生理作用

在脑膜中由 PIP 在 PIP 激酶作用下形成;涉及受体激活磷脂酶 C 机理的组分;体外刺激脑磷脂酶 D。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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Shanjin Huang et al.
Molecular biology of the cell, 17(4), 1946-1958 (2006-01-27)
The cytoskeleton is a key regulator of morphogenesis, sexual reproduction, and cellular responses to extracellular stimuli. Changes in the cellular architecture are often assumed to require actin-binding proteins as stimulus-response modulators, because many of these proteins are regulated directly by
Sophie Lev et al.
Infection and immunity, 81(4), 1245-1255 (2013-02-06)
Phospholipase C (PLC) of Cryptococcus neoformans (CnPlc1) is crucial for virulence of this fungal pathogen. To investigate the mechanism of CnPlc1-mediated signaling, we established that phosphatidylinositol 4,5-bisphosphate (PIP(2)) is a major CnPlc1 substrate, which is hydrolyzed to produce inositol trisphosphate
Euripedes de Almeida Ribeiro et al.
Cell, 159(6), 1447-1460 (2014-12-01)
The spectrin superfamily of proteins plays key roles in assembling the actin cytoskeleton in various cell types, crosslinks actin filaments, and acts as scaffolds for the assembly of large protein complexes involved in structural integrity and mechanosensation, as well as

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