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一般描述
磷脂酸是在磷脂酶D的作用下由磷脂酰胆碱获得的。
应用
3-sn-磷脂酸钠盐（来自蛋黄卵磷脂）
- 可用于CDS（胞苷三磷酸：磷脂酸胞苷酰转移酶）分析的反应混合物及作为薄层色谱(TLC)的参考磷脂
- 作为鉴定反应生成的放射性标记磷脂酸(PA)的对照标准品
- 研究其对At-Rac2相关激酶活性的影响
生化/生理作用
磷脂酸可用作吞噬细胞呼吸爆发的调节剂。它也是二酰基甘油、磷脂酸和溶血磷脂酸的前体。
特点和优势
该化合物是环核苷酸研究的特色产品。 点击此处 ，发现更多特色环核苷酸产品。。在 sigma.com/discover-bsm了解更多关于其他研究领域的生物活性小分子。
制备说明
由 L -α 制备-用卷心菜磷脂酶 D 水解磷脂酰胆碱。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Daniel Pastor-Flores et al.
Biochimica et biophysica acta, 1861(3), 249-259 (2016-01-09)
Pkh is the yeast ortholog of the mammalian 3-phosphoinositide-dependent protein kinase 1 (PDK1). Pkh phosphorylates the activation loop of Ypks, Tpks, Sch9 and also phosphorylates the eisosome components Lsp1 and Pil1, which play fundamental roles upstream of diverse signaling pathways
Stefano Mancuso et al.
Plant signaling & behavior, 2(4), 240-244 (2007-07-01)
Auxin (IAA) is versatile signalling molecule of plants, currently classified as plant hormone. But there are data suggesting that auxin is acting also as plant-specific morphogen, electric-responses inducing transmitter, and as general signalling molecule used for plant-bacteria communication. Our previous
Phosphatidic acid and phospholipase D both stimulate phosphoinositide turnover in cultured human keratinocytes
Ryder NS, et al.
Cellular Signalling, 5(6), 787-794 (1993)
Alexandre Francou et al.
Development (Cambridge, England), 141(22), 4320-4331 (2014-11-06)
Elongation of the vertebrate heart occurs by progressive addition of second heart field (SHF) cardiac progenitor cells from pharyngeal mesoderm to the poles of the heart tube. The importance of these cells in the etiology of congenital heart defects has
Glycerolipids in signal transduction
Lambeth JD, et al.
New Biotechnology, 31, 237-255 (1996)
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Cyclic nucleotides like cAMP modulate cell function via PKA activation and ion channels.
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