所有图片(1)
别名:
4-Methoxy-N,N′-bis(3-pyridinylmethyl)-1,3-benzenedicarboxamide
经验公式（希尔记法）:
C21H20N4O3
CAS号:
分子量:
376.41
EC 号:
MDL编号:
UNSPSC代码:
12352204
PubChem化学物质编号:
NACRES:
NA.83
推荐产品
检测方案
≥98%
质量水平
形式
powder
溶解性
ethanol: 50 mg/mL, clear, colorless to light yellow
SMILES字符串
COc1ccc(cc1C(=O)NCc2cccnc2)C(=O)NCc3cccnc3
InChI
1S/C21H20N4O3/c1-28-19-7-6-17(20(26)24-13-15-4-2-8-22-11-15)10-18(19)21(27)25-14-16-5-3-9-23-12-16/h2-12H,13-14H2,1H3,(H,24,26)(H,25,27)
InChI key
KYWCWBXGRWWINE-UHFFFAOYSA-N
基因信息
human ... TBXA2R(6915)
生化/生理作用
Eicosenoid receptor antagonist; a thromboxane A2 antagonist; antiplatelet agent.
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
P L Malini et al.
Lancet (London, England), 350(9070), 15-18 (1997-07-05)
The increased prostaglandin synthesis that might follow stimulation of the arachidonic acid cascade by angiotensin-converting-enzyme inhibition (ACE-I) has been suggested to underlie the appearance of cough on ACE-I treatment. We investigated whether the prostanoid thromboxane was involved. Nine patients with
Matthew Hotston et al.
BJU international, 106(11), 1794-1798 (2010-05-27)
To explore the possible role of of 8-isoprostane F(2α) (8-IPF(2α) ) in the aetiology of erectile dysfunction (ED), as the over-production of superoxide (O(2)(-)) derived from nicotinamide adenine dinucleotide phosphate (NADPH) oxidase results in the formation of 8-IPF(2α) in vascular
G D'Andrea et al.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 27 Suppl 2, S96-S99 (2006-05-12)
Migraine with aura (MwA) sufferers, at times, need specific treatments. This is the case when the auras are frequent, prolonged and cause anxiety and distress. Abnormal release of glutamate, which may trigger auras, and abnormal platelet behaviour, which constitutes a
W Van Molle et al.
FEBS letters, 467(2-3), 201-205 (2000-02-17)
Tumor necrosis factor (TNF) induces hepatitis when injected in human beings or in rodents. The molecular mechanism by which TNF induces hepatic distress remains largely unknown, although induction of apoptosis of hepatocytes appears to be an essential step. In order
M Berrettini et al.
European journal of clinical pharmacology, 39(5), 495-500 (1990-01-01)
Picotamide (G 137), a new non prostanoid inhibitor of in vitro arachidonic acid induced platelet aggregation, has been further characterized in in vitro and ex vivo studies. When whole blood was activated with collagen in the presence of picotamide 5
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