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Merck
CN

P8023

磷脂酶 D 来源于色褐链霉菌

lyophilized powder, ≥2,000 units/mg solid

别名:

Phosphatidylcholine phosphatidohydrolase, 卵磷脂酶 D

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化学文摘社编号:
UNSPSC Code:
41106300
EC Number:
232-639-8
MDL number:
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form

lyophilized powder

specific activity

≥2,000 units/mg solid

composition

Protein, ~50% Lowry

storage temp.

−20°C

Biochem/physiol Actions

磷脂酶 D 对鞘磷脂和溶血磷脂有活性。磷脂酶 D 水解磷脂和鞘磷脂的磷酸键,得到相应的的磷脂酸。

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

One unit will liberate 1.0 μM of choline from L-α-phosphatidylcholine (egg yolk) per hr at pH 8.0 at 30°C.

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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N S Ryder et al.
Cellular signalling, 5(6), 787-794 (1993-11-01)
Phosphatidic acid (PA) induced a rapid dose-dependent increase in production of inositol phosphates in cultured adult human keratinocytes, peaking at 30 s. Natural and dioleoyl PA were equally effective, while other phospholipid classes had no effect. Lipid A was also
Viviana Trezza et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(43), 14899-14908 (2012-10-27)
The brain endocannabinoid system plays a crucial role in emotional processes. We have previously identified an important role for endocannabinoids in social play behavior, a highly rewarding form of social interaction in adolescent rats. Here, we tested the hypothesis that
Anna O Müller et al.
Chemistry and physics of lipids, 165(7), 787-793 (2012-10-13)
Cardiolipin (CL) and related diphosphatidyl lipids are hardly accessible because of the complexity of their chemical synthesis. In the present paper, the transphosphatidylation reaction catalyzed by phospholipase D (PLD) from Streptomyces sp. has been proven as an alternative enzyme-assisted strategy
Fumiyuki Sanematsu et al.
The Journal of biological chemistry, 288(12), 8092-8100 (2013-01-31)
Activation of receptor tyrosine kinases leads to the formation of two different types of plasma membrane structures: peripheral ruffles and dorsal ruffles. Although the formation of both ruffle types requires activation of the small GTPase Rac, the difference in kinetics
Wahida H Ali et al.
PloS one, 8(1), e55325-e55325 (2013-02-06)
Cell migration and phagocytosis ensue from extracellular-initiated signaling cascades that orchestrate dynamic reorganization of the actin cytoskeleton. The reorganization is mediated by effector proteins recruited to the site of activity by locally-generated lipid second messengers. Phosphatidic acid (PA), a membrane

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