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关于此项目
线性分子式:
C6H5CH2N(CH3)CH2C≡CH·HCl
化学文摘社编号:
分子量:
195.69
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
206-175-1
MDL number:
Beilstein/REAXYS Number:
3699487
产品名称
Pargyline 盐酸盐,
biological source
synthetic
Quality Level
assay
98% (TLC)
form
powder or crystals
mp
160-163 °C (lit.)
solubility
water: 50 mg/mL, clear, colorless to faintly yellow
storage temp.
−20°C
SMILES string
Cl[H].CN(CC#C)Cc1ccccc1
InChI
1S/C11H13N.ClH/c1-3-9-12(2)10-11-7-5-4-6-8-11;/h1,4-8H,9-10H2,2H3;1H
InChI key
BCXCABRDBBWWGY-UHFFFAOYSA-N
Gene Information
human ... MAOA(4128), MAOB(4129)
Application
优降宁盐酸盐已用于:
- 用作组蛋白脱甲基酶抑制剂来治疗单核细胞,以研究各种抑制剂是否会影响训练
- 以最大程度地吸收实验大鼠的多巴胺能神经元(DA)神经元,
- 以研究其对核盘菌菌核髓质组织变色的影响
Biochem/physiol Actions
优降宁盐酸盐可用作组蛋白脱甲基酶抑制剂。它具有抗高血压作用。
选择性 MAO-B 抑制剂。
signalword
Danger
hcodes
pcodes
Hazard Classifications
Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Biochemical Pathway for the Formation of Abnormal Sclerotia of Sclerotinia sclerotiorum
Huang HC and Yeung JM
Plant Pathology, 11(1), 2-2 (2002)
Trained immunity or tolerance: opposing functional programs induced in human monocytes after engagement of various pattern recognition receptors
Ifrim DC, et al.
Clinical and Vaccine Immunology : CVI, 21(4), 534-545 (2014)
Resonant antidromic cortical circuit activation as a consequence of high-frequency subthalamic deep-brain stimulation
Li S, et al.
Journal of Neurophysiology, 98(6), 3525-3537 (2007)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| P8013-5G | 04061832948508 |
| P8013-1G | 04061834400769 |
| P8013-500MG | 04061832948492 |
