所有图片(4)
About This Item
线性分子式:
C4H8N3O5PNa2 · x H2O
CAS号:
分子量:
255.08 (anhydrous basis)
EC 号:
MDL编号:
UNSPSC代码:
12352204
PubChem化学物质编号:
NACRES:
NA.32
product name
磷酸肌酸 二钠盐 水合物, ≥97%
质量水平
检测方案
≥97%
形式
powder
杂质
≤0.02% free creatine
颜色
white
溶解性
water: 50 mg/mL, clear, colorless
储存温度
−20°C
SMILES字符串
O.[Na+].[Na+].CN(CC(O)=O)C(=N)NP([O-])([O-])=O
InChI
1S/C4H10N3O5P.2Na.H2O/c1-7(2-3(8)9)4(5)6-13(10,11)12;;;/h2H2,1H3,(H,8,9)(H4,5,6,10,11,12);;;1H2/q;2*+1;/p-2
InChI key
KZVYPOKBYRXZKS-UHFFFAOYSA-L
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应用
磷酸肌酸二钠盐水合物已用于：
- 作为爪蟾缓冲液(XB)组分，用于去除膜吸附性蛋白质
- 作为M5+缓冲液组分，进行极化全内反射荧光(polTIRF)实验
- 作为ATP再生系统组分，用于7-硝基-2-1,3-苯并噁二唑-4-基磷脂(NBD-PL)转位检测
生化/生理作用
磷酸肌酸(Phosphocreatine)因其在肌酸激酶作用下的最快再生形式而广为人知，起到临时能量缓冲器的作用。磷酸肌酸存在于肌肉组织中，在维持肌肉细胞的能量稳态中起重要作用。
磷酸肌酸二钠盐水合物可用于研究鼻咽癌细胞和诱发的暂时性心脏骤停。它也用于评估伏隔核中腺苷A(2A)受体调节对大鼠可卡因寻求行为的影响。
磷酸肌酸是脊椎动物和某些无脊椎动物肌肉的高能磷酸基储蓄池，提供ADP-ATP转换所需磷酸。
制备说明
酶法制备。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Cyril Bernis et al.
Methods in cell biology, 122, 165-191 (2014-05-27)
The large and complex eukaryotic nucleus is the arbiter of DNA replication, RNA transcription, splicing, and ribosome assembly. With the advent of in vitro nuclear reconstitution extracts derived from Xenopus eggs in the 1980s, it became possible to assemble multiple
Casey E O'Neill et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 37(5), 1245-1256 (2011-12-16)
Repeated cocaine administration enhances dopamine D(2) receptor sensitivity in the mesolimbic dopamine system, which contributes to drug relapse. Adenosine A(2A) receptors are colocalized with D(2) receptors on nucleus accumbens (NAc) medium spiny neurons where they antagonize D(2) receptor activity. Thus
Protective effects of a magnesium magnetic isotope (Mg(25) )-exchanging nanoparticle ((25) MgPMC(16) ) on mitochondrial functional disorders in esmolol-induced cardiac arrest in rats
Adeli, S., et al.
Auton. Autocoid Pharmacol., 32, 1-7 (2012)
John F Beausang et al.
Biophysical journal, 104(6), 1263-1273 (2013-03-27)
Myosin V is biomolecular motor with two actin-binding domains (heads) that take multiple steps along actin by a hand-over-hand mechanism. We used high-speed polarized total internal reflection fluorescence (polTIRF) microscopy to study the structural dynamics of single myosin V molecules
Lucas Guimarães-Ferreira
Einstein (Sao Paulo, Brazil), 12(1), 126-131 (2014-04-15)
Adenosine triphosphate is the present energy currency in the body, and is used in various cellular and indispensable processes for the maintenance of cell homeostasis. The regeneration mechanisms of adenosine triphosphate, from the product of its hydrolysis - adenosine diphosphate
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