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关于此项目
经验公式(希尔记法):
C16H17KN2O4S
化学文摘社编号:
分子量:
372.48
PubChem Substance ID:
eCl@ss:
34010400
UNSPSC Code:
12352207
NACRES:
NA.76
EC Number:
204-038-0
MDL number:
Beilstein/REAXYS Number:
3832841
产品名称
青霉素G 钾盐, powder, BioReagent, suitable for cell culture
InChI key
IYNDLOXRXUOGIU-LQDWTQKMSA-M
InChI
1S/C16H18N2O4S.K/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1
SMILES string
[K+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)Cc3ccccc3)C([O-])=O
product line
BioReagent
form
powder
potency
1440-1680 units per mg
technique(s)
cell culture | mammalian: suitable
antibiotic activity spectrum
Gram-positive bacteria
mode of action
cell wall synthesis | interferes
Quality Level
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General description
Chemical structure: β-lactam
Biochem/physiol Actions
作用机制:青霉素G通过与青霉素结合蛋白(PBP)结合抑制肽聚糖链交联,从而抑制细胞壁合成。
抗菌谱:本品具有抗革兰氏阳性菌和革兰氏阴性菌活性。
抗菌谱:本品具有抗革兰氏阳性菌和革兰氏阴性菌活性。
Application
Penicillin G is a narrow spectrum antibiotic derived from Streptococcus pneumoniae. It is the drug of choice for groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridians group streptococci, and non-penicillinase producing staphylococcus. The potassium salt has been used to study murosomes of staphylococci and the penicillin-induced lysis of Streptococcus mutans.
Disclaimer
Solutions should be filter sterilized and stored at 2-8°C for 1 week or at -20°C for more lengthy periods. Solutions are stable at 37°C for 3 days. The potassium salt is soluble in H2O at 100 mg/mL.
Other Notes
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
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