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Merck
CN

P7794

青霉素G 钾盐

powder, suitable for cell culture, BioReagent

别名:

苄青霉素 钾盐

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关于此项目

经验公式(希尔记法):
C16H17KN2O4S
化学文摘社编号:
分子量:
372.48
PubChem Substance ID:
eCl@ss:
34010400
UNSPSC Code:
12352207
NACRES:
NA.76
EC Number:
204-038-0
MDL number:
Beilstein/REAXYS Number:
3832841
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产品名称

青霉素G 钾盐, powder, BioReagent, suitable for cell culture

InChI key

IYNDLOXRXUOGIU-LQDWTQKMSA-M

InChI

1S/C16H18N2O4S.K/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1

SMILES string

[K+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)Cc3ccccc3)C([O-])=O

product line

BioReagent

form

powder

potency

1440-1680 units per mg

technique(s)

cell culture | mammalian: suitable

antibiotic activity spectrum

Gram-positive bacteria

mode of action

cell wall synthesis | interferes

Quality Level

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General description

Chemical structure: β-lactam

Biochem/physiol Actions

作用机制:青霉素G通过与青霉素结合蛋白(PBP)结合抑制肽聚糖链交联,从而抑制细胞壁合成。

抗菌谱:本品具有抗革兰氏阳性菌和革兰氏阴性菌活性。

Application

Penicillin G is a narrow spectrum antibiotic derived from Streptococcus pneumoniae. It is the drug of choice for groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridians group streptococci, and non-penicillinase producing staphylococcus. The potassium salt has been used to study murosomes of staphylococci and the penicillin-induced lysis of Streptococcus mutans.

Disclaimer

Solutions should be filter sterilized and stored at 2-8°C for 1 week or at -20°C for more lengthy periods. Solutions are stable at 37°C for 3 days. The potassium salt is soluble in H2O at 100 mg/mL.

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

pictograms

Exclamation mark

signalword

Warning

hcodes

pcodes

Hazard Classifications

Skin Sens. 1

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

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分析证书(COA)

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