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Merck
CN

P7568

Sigma-Aldrich

β-乙酰基-γ-O-烷基-L-α-磷脂酰胆碱 来源于牛心脏卵磷脂

≥99%, lyophilized powder

别名:

1-O-烷基-2-乙酰基-sn-甘油-3-磷酸胆碱, 2-乙酰基-1-烷基-sn-甘油-3-磷酸胆碱, AcGEPC, PAF, 血小板活化因子

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About This Item

CAS号:
Beilstein:
4220745
MDL编号:
UNSPSC代码:
12352211
PubChem化学物质编号:
NACRES:
NA.77

质量水平

检测方案

≥99%

形式

lyophilized powder

储存温度

−20°C

SMILES字符串

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(C)=O)COCCCCCCCCCCCCCCCC)=O

InChI

1S/C26H54NO7P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-31-23-26(34-25(2)28)24-33-35(29,30)32-22-20-27(3,4)5/h26H,6-24H2,1-5H3/t26-/m1/s1

InChI key

HVAUUPRFYPCOCA-AREMUKBSSA-N

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相关类别

生化/生理作用

淋巴细胞、血小板和内皮细胞产生的磷脂,可以诱导血小板聚集,与炎症、过敏以及创伤愈合有关。

包装

在氩气下包装。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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F Bussolino et al.
Cell calcium, 5(5), 463-473 (1984-10-01)
Platelet-activating factor (1-0-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine, PAF) is a potent inducer of shape-change, aggregation and secretion in platelets. PAF causes a rapid increase in intracellular calcium, but has no calcium gating effect in intact lipid bilayers. Human red cells (RBC) did not metabolize
Julie R Jin et al.
Frontiers in immunology, 11, 585070-585070 (2020-11-17)
Mast cells are the major effector cells in immunoglobulin E (IgE)-mediated allergy. The high affinity IgE receptor FcεRI, as well as G protein-coupled receptors (GPCRs) on the mast cell surface signals to phosphoinositide 3-kinase γ (PI3Kγ) to initiate degranulation, cytokine
Stephanie Saul et al.
Journal of leukocyte biology, 106(5), 1101-1115 (2019-06-20)
Neutrophils play a central role in immunity and inflammation via their intrinsic ability to migrate into inflamed tissue, to phagocytose pathogens, and to kill bacterial and fungi by releasing large quantities of superoxide anions and lytic enzymes. The molecular pathways

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