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一般描述
磷酸(烯醇)丙酮酸(PEP)可作为抑制剂,抑制己糖激酶、磷酸葡萄糖异构酶、磷酸果糖激酶和醛缩酶。它是一种双官能碳水化合物,具有抗氧化特性。PEP可能是临床移植领域潜在的器官保存剂。
应用
磷酸(烯醇)丙酮酸单钾盐用于:
- 保持三磷酸腺苷(ATP)的浓度恒定,组装活性凝胶
- 作为检测缓冲液成分,用于 体外 ATP酶检测
- 作为储备溶液,用于光陷俘测定
生化/生理作用
磷酸(烯醇)丙酮酸 (PEP) 参与糖酵解和糖异生。在糖酵解中,PEP 被丙酮酸激酶代谢生成丙酮酸。在植物中,PEP 参与芳香族氨基酸的形成以及碳固定途径。
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
从最新的版本中选择一种:
分析证书(COA)
Single Molecule Analysis (2018)
Proceedings of the National Academy of Sciences of the United States of America, 78(9), 5588-5592 (1981-09-01)
A serum-free, hormone-supplemented medium, enriched with a mixture of lipids, has been developed that supports rapid clonal growth of human diploid fetal lung fibroblasts (Flow 2000, WI-38, MRC-5, and IMR-90) and of low-passage human foreskin fibroblasts. The medium, which contains
Phosphoenolpyruvic acid, an intermediate of glycolysis, attenuates cellular injury induced by hydrogen peroxide and 2-deoxy-D-glucose in the porcine proximal kidney tubular cell line, LLC-PK1
Journal of Health Science, 56(6), 727-732 (2010)
N-terminal polar amino acids of the C2 insert of nonmuscle myosin II-C2 regulate its functional properties
Febs Letters, 590(23), 4223-4232 (2016)
Methods in molecular biology (Clifton, N.J.), 447, 381-394 (2008-03-29)
Chronic alcohol consumption has been shown to severely compromise mitochondrial protein synthesis. Hepatic mitochondria isolated from alcoholic animals contain decreased levels of respiratory complexes and display depressed respiration rates when compared to pair-fed controls. One underlying mechanism for this involves
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Warburg effect enhances glucose to lactate conversion in tumor cells, regardless of oxygen levels; impacting cancer metabolism since 1924.
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