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Merck
CN

P6972

Sigma-Aldrich

Monoclonal Anti-Interferon-γ−R-Phycoerythrin antibody produced in mouse

clone 25723, purified immunoglobulin, saline solution

别名:

Monoclonal Anti-Interferon-γ

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About This Item

UNSPSC代码:
51111800
NACRES:
NA.41

生物来源

mouse

质量水平

偶联物

phycoerythrin (R-PE) conjugate

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

25723, monoclonal

表单

saline solution

种属反应性

human

技术

flow cytometry: suitable

同位素/亚型

IgG2b

UniProt登记号

运输

wet ice

储存温度

2-8°C

基因信息

human ... IFNG(3458)

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一般描述

Human Interferon-γ (IFN-γ) is a Type I cytokine produced by the lymphocytes activated in response to specific antigens or mitogens. It has a pivotal role in activating primed macrophages for nonspecific tumoricidal activity as well as can stimulate monocytes for enhanced cytotoxicity against tumor cells. It also has several biological functions like inhibition of cell or tumor growth, promotion of B cell differentiation into plasma cells and antiviral activity. Further, it can enhance the cytotoxicity of natural killer cells and T-cells. Monoclonal anti-Interferon-γ−R-Phycoerythrin antibody reacts specifically with human IFN-γ.

特异性

The conjugates will identify and quantitate cells containing intracellular forms of human IFN-γ by flow cytometry.

免疫原

recombinant human IFN-γ

应用

Monoclonal anti-Interferon-γ−R-Phycoerythrin antibody can be used in flow cytometry for detecting intracytoplasmic cytokines and enumerating cytokine-producing cells in a mixed population.

外形

Solution in saline containing up to 0.5% bovine serum albumin and 0.1% sodium azide as a preservative.

制备说明

Purified antibody is conjugated to R-phycoerythrin (PE).

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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分析证书(COA)

Lot/Batch Number

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Jamie R Schoenborn et al.
Advances in immunology, 96, 41-101 (2007-11-06)
Interferon-gamma (IFN-gamma) is crucial for immunity against intracellular pathogens and for tumor control. However, aberrant IFN-gamma expression has been associated with a number of autoinflammatory and autoimmune diseases. This cytokine is produced predominantly by natural killer (NK) and natural killer

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