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Merck
CN

P6621

Sigma-Aldrich

磷脂酶 C 来源于蜡样芽胞杆菌

greener alternative

≥200 units/mg protein

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别名:
PC-PLC, 卵磷脂酶 C, 磷脂二酯酶 I, 磷脂酰胆碱胆碱磷酸水解酶
CAS号:
MDL编号:
UNSPSC代码:
12352204
NACRES:
NA.54

形式

lyophilized powder

质量水平

比活

≥200 units/mg protein

分子量

23-27 kDa by SDS-PAGE

环保替代产品特性

Waste Prevention
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

溶解性

H2O: soluble 1.0 mg/mL, faintly hazy to hazy

环保替代产品分类

储存温度

−20°C

基因信息

Bacillus cereus ATCC 10987 ... plC(2749087)

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一般描述

我们致力于为您带来更加绿色的替代产品,这些产品遵守一项或多项绿色化学12项原则。当用于生物柴油研究时,该产品的能效和废物预防能力已被增强。有关详细信息,请参阅 《Biofiles》的文章

应用

来自Sigma的酶已用于消化曼氏血吸虫成虫的磷脂酰丝氨酸部分。
磷脂酶C(PLC)可用于研究肾上腺素能受体介导的跨膜信号传导。它可用于降解含肌醇的磷脂。来自芽孢杆菌的磷脂酶C,产品P6621,已用于研究flhF是如何影响PLC和其他分泌性毒力因子的输出

生化/生理作用

磷脂酶C可由凝血酶和血小板活化因子诱导形成1,2-二酰基甘油和磷脂酸。PLC可水解磷脂酰胆碱和其他甘油磷脂上的磷酸键,产生二酰基甘油;这种酶还可水解鞘磷脂、心磷脂、胆碱缩醛磷脂和神经酰胺磷脂的磷酸键。
水解磷脂酰胆碱和其他甘油磷脂的磷酸键生成甘油二酯;该酶也可水解鞘磷脂、心磷脂、胆碱缩醛磷脂以及神经酰胺磷脂的磷酸键。

单位定义

在pH 7.3、37 °C条件下,一单位在每分钟内可从L-α-磷脂酰胆碱释放1.0 μ摩尔的水溶性有机磷。

外形

含有约10%蛋白的冻干粉末。剩余;海藻糖、硫酸锌和磷酸钾

象形图

Health hazard

警示用语:

Danger

危险声明

预防措施声明

危险分类

Resp. Sens. 1

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

常规特殊物品

分析证书(COA)

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Schistosome infections are characterized by prominent T cell hyporesponsiveness during the chronic stage of infection. We found that schistosome-specific phosphatidylserine (PS) activated TLR2 and affected dendritic cells such that mature dendritic cells gained the ability to induce the development of
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The present study compares the molecular mechanism by which thrombin, platelet-activating factor, and epinephrine induce platelet activation. Thrombin and platelet-activating factor induce an initial activation of phospholipase C, as measured by formation of 1,2-diacylglycerol and phosphatidic acid, during platelet shape
Zollner, H.
Handbook of Enzyme Inhibitors, 387-387 (1993)

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