生物来源
synthetic (organic)
质量水平
检测方案
≥99%
形式
powder
官能团
ester
脂质类型
phosphoglycerides
运输
ambient
储存温度
−20°C
SMILES字符串
[H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O.[Na+]
InChI
1S/C34H67O10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-33(37)41-29-32(30-43-45(39,40)42-28-31(36)27-35)44-34(38)26-24-22-20-18-16-14-12-10-8-6-4-2;/h31-32,35-36H,3-30H2,1-2H3,(H,39,40);/q;+1/p-1/t31?,32-;/m1./s1
InChI key
QLNOOKSBAYIHQI-SKZICHJRSA-M
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一般描述
1,2-二肉豆蔻酰基-sn-甘油-3-磷酸-rac-(1-甘油)钠盐(DMPG)是含有阴离子饱和磷脂的14C原子。它主要存在于革兰氏阳性细菌膜中,并包含两条链。为了模拟细菌膜,将DMPG与两性离子磷脂结合。在低盐下,DMPG在凝胶相和液相中形成渗漏的囊泡。它在高盐下显示出凝胶−流体转变。DMPG用作肽−脂相互作用研究和基于温度的膜结构研究的模型系统。
应用
1,2-二肉豆蔻酰基-sn-甘油-3-磷酸-rac-(1-甘油)钠盐用作反相高效液相色谱法(RP-HPLC)的内标。它还被用作扩散研究泡沫薄膜(FFs)的组成部分。
用于制备带有带负电荷的亲水性头基的脂质体的原型。化学计量量(1:2)的二价阳离子的存在强烈影响相变、紧密堆积比和离子渗透性。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
The peculiar thermo-structural behavior of the anionic lipid DMPG
Chemistry and Physics of Lipids, 122(1-2), 19-32 (2003)
Aqueous dispersions of DMPG in low salt contain leaky vesicles
Chemistry and Physics of Lipids, 165(2), 169-177 (2012)
Effects of pure n-alkanes and crude oil on bacterial phospholipid classes and molecular species determined by electrospray ionization mass spectrometry
Journal of Chromatography. B, Biomedical Sciences and Applications, 822(1-2), 40-53 (2005)
Molecular mobility in the monolayers of foam films stabilized by porcine lung surfactant
Biophysical Journal, 71(5), 2591-2601 (1996)
Langmuir : the ACS journal of surfaces and colloids, 31(30), 8386-8391 (2015-07-15)
Nanodisc films are a promising approach to study the equilibrium conformation of membrane bound proteins in native-like environment. Here we compare nanodisc formation for NADPH-dependent cytochrome P450 oxidoreductase (POR) using two different scaffold proteins, MSP1D1 and MSP1E3D1. Despite the increased
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