一般描述
蛋白酶广泛存在于自然界，微生物是这些酶的良好来源。它们分为四类，即天冬氨酸、丝氨酸、半胱氨酸和金属蛋白酶。
应用
来源于芽孢杆菌的蛋白酶已被用于通过分光光度法测定其蛋白水解活性。
生化/生理作用
蛋白酶通过肽键的水解使蛋白质分解代谢。蛋白酶可被丝氨酸活性位点抑制剂所灭活，如苯甲基磺酰氟（PMSF）和二异丙基氟磷酸盐。 芽孢杆菌分泌的蛋白酶分子量通常为20,000至30,000。Ca2+通常对它们有稳定作用，它们的等电点较高。 它在较宽的pH 值和温度范围内易溶于洗涤剂。蛋白酶可通过高效地清除伤口的坏死物质而改善愈合过程。它广泛应用于衣物清洗剂，用于清除衣物上的蛋白质类污迹。此外，蛋白酶也用于食品、药物、皮革和丝绸行业。它是生物药物产品（包括隐形眼镜酶清洁剂和酶清洗剂）的关键成分。蛋白酶也促进多个生理过程，如蛋白质更新、消化、凝血、受精和细胞分化。它也促进生长、细胞信号传导、免疫反应和细胞凋亡。
法律信息
Novozyme公司产品。
警示用语：
Danger
危险声明
危险分类
Aquatic Chronic 3 - Eye Dam. 1 - Resp. Sens. 1
WGK
WGK 2
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
常规特殊物品
Irreversible inhibitors of serine, cysteine, and threonine proteases
Powers JC, et al.
Chemical Reviews, 102(12), 4639-4750 (2002)
Isolation, production and characterization of protease from Bacillus sp. isolated from soil sample
Josephine FS, et al.
Journal of Microbiology, 2(1), 163-168 (2012)
Effect of UV light on microbial proteases: From enzyme inactivation to antioxidant mitigation.
Lante A, et al.
Innovative Food Science & Emerging Technologies, 17, 130-134 (2013)
M Du et al.
Journal of animal science, 85(4), 919-927 (2006-12-21)
Mammalian target of rapamycin (mTOR) signaling is one of the main signaling pathways controlling protein synthesis. Leucine treatment upregulates mTOR signaling, which enhances protein synthesis; however, the mechanisms are not well understood. Herein, treatment of C2C12 myoblast cells with leucine
Nicolas Buchon et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(30), 12442-12447 (2009-07-11)
The Drosophila Toll receptor does not interact directly with microbial determinants, but is instead activated by a cleaved form of the cytokine-like molecule Spätzle. During the immune response, Spätzle is processed by complex cascades of serine proteases, which are activated
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门