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Merck
CN

P5874

Sigma-Aldrich

PTACH

≥98% (HPLC), solid

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别名:
Cpd 51, S-[6-(4-Phenyl-2-thiazolylcarbamoyl)hexyl] thioisobutyrate
经验公式(希尔记法):
C20H26N2O2S2
分子量:
390.56
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77

检测方案

≥98% (HPLC)

形式

solid

溶解性

DMSO: 26 mg/mL

储存温度

2-8°C

SMILES字符串

CC(C)C(=O)SCCCCCCC(=O)Nc1nc(cs1)-c2ccccc2

InChI

1S/C20H26N2O2S2/c1-15(2)19(24)25-13-9-4-3-8-12-18(23)22-20-21-17(14-26-20)16-10-6-5-7-11-16/h5-7,10-11,14-15H,3-4,8-9,12-13H2,1-2H3,(H,21,22,23)

InChI key

MDYDGUOQFUQOGE-UHFFFAOYSA-N

生化/生理作用

HDAC inhibitor; more potent than the majority of HDAC inhibitors except for SAHA (gold standard).

特点和优势

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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Minghui Wang et al.
Neuron, 109(2), 257-272 (2020-11-26)
To identify the molecular mechanisms and novel therapeutic targets of late-onset Alzheimer's Disease (LOAD), we performed an integrative network analysis of multi-omics profiling of four cortical areas across 364 donors with varying cognitive and neuropathological phenotypes. Our analyses revealed thousands

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