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Merck
CN

P5687

Sigma-Aldrich

Monoclonal Anti-Prostatic Acid Phosphatase, Human antibody produced in mouse

clone PAP-12, ascites fluid

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About This Item

MDL编号:
UNSPSC代码:
12352203
NACRES:
NA.46

生物来源

mouse

质量水平

偶联物

unconjugated

抗体形式

ascites fluid

抗体产品类型

primary antibodies

克隆

PAP-12, monoclonal

包含

15 mM sodium azide

种属反应性

human

技术

indirect ELISA: 1:800 using purified preparation of human prostatic acid phosphatase

同位素/亚型

IgG1

UniProt登记号

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... ACPP(55)

一般描述

The antibodies localize the 48 kDa subunit of prostatic acid phosphatase in immunoblotting, using reducing and denaturing conditions, without cross-reactivity to prostate specific antigen or other human serum or tissue proteins.

免疫原

human prostatic acid phosphatase

生化/生理作用

Prostatic acid phosphatase (PAP) is a non-specific phosphomonoesterase synthesized in prostate epithelial cells. The major function of PAP is the regulation of prostate cell growth. The levels of PAP serve as marker for prostate cancer progression. PAP has been reported to exhibit antinociceptive effect in neuropathic and inflammatory pain that is characteristic of cancer-induced bone pain.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Lei Chen et al.
Pain physician, 16(6), 533-546 (2013-11-29)
Cancer-induced bone pain (CIBP) is a severe chronic pain that is less than adequately controlled by conventional analgesics. Prostatic acid phosphatase (PAP) has been considered as a diagnostic marker for prostate cancer and its transmembrane isoform has been reported to
Hoon Young Kong et al.
Biomolecules & therapeutics, 21(1), 10-20 (2013-09-07)
Prostate cancer is one of the most prevalent non-skin related cancers. It is the second leading cause of cancer deaths among males in most Western countries. If prostate cancer is diagnosed in its early stages, there is a higher probability
Paulo R Bueno et al.
Nanoscale, 9(40), 15362-15370 (2017-10-04)
The application of nanoscale capacitance as a transduction of molecular recognition relevant to molecular diagnostics is demonstrated. The energy-related signal relates directly to the electron occupation of quantized states present in readily fabricated molecular junctions such as those presented by

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