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P5172

前列腺素 D 2

synthetic, ≥95%, adenylyl cyclase stimulator, powder

别名:

(5Zα13E,15S)-9,15-二羟基-11-氧代前列素-5,13-二烯-1-酸, 前列腺素 d 2

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关于此项目

经验公式（希尔记法）:
C20H32O5
化学文摘社编号:
41598-07-6
分子量:
352.47
UNSPSC Code:
12352211
eCl@ss:
42020658
PubChem Substance ID:
24898605
NACRES:
NA.77
Beilstein/REAXYS Number:
2170623
MDL number:
MFCD00077857
Assay:
≥95%
Form:
powder
Quality level:
100
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产品名称

前列腺素 D 2, ≥95%, synthetic

biological source

synthetic

Quality Level

100

assay

≥95%

form

powder

storage temp.

−20°C

SMILES string

[H][C@]1(C\C=C/CCCC(O)=O)[C@@H](O)CC(=O)[C@]1([H])\C=C\[C@@H](O)CCCCC

InChI

1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-18,21-22H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-/m0/s1

InChI key

BHMBVRSPMRCCGG-OUTUXVNYSA-N

Biochem/physiol Actions

脑内主要的前列腺素；诱发炎症；刺激腺苷酸环化酶。

Features and Benefits

《受体分类和信号转导》手册的 前列腺素类受体 页面有该化合物的介绍。想要浏览手册的其他页面， 请单击此处。

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pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

hcodes

H302,H360

Hazard Classifications

Acute Tox. 4 Oral - Repr. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCT9569
MKCQ9648
MKCQ4174
MKCP0239
MKCD7725

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Luzheng Xue et al.
The Journal of allergy and clinical immunology, 133(4), 1184-1194 (2014-01-07)
Activation of the group 2 innate lymphoid cell (ILC2) population leads to production of the classical type 2 cytokines, thus promoting type 2 immunity. Chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2), a receptor for prostaglandin D₂ (PGD₂), is expressed
Alon Mantel et al.
The Journal of investigative dermatology, 132(4), 1103-1110 (2011-12-16)
Aldo-keto reductase 1C3 (AKR1C3) has been shown to mediate the metabolism of sex hormones and prostaglandin D(2) (PGD(2)), a lipid mediator that promotes skin inflammation in atopic dermatitis (AD). As both have a role in skin function and pathology, we
L S Wolfe et al.
Journal of neurochemistry, 53(1), 64-70 (1989-07-01)
In homogenates of rat cerebral neocortex prostaglandin D2 (PGD2) was found to be quantitatively the main PG biosynthesized by a cytosolic PGD synthetase from endogenously released arachidonic acid. Amounts of 628 ng/g wet weight were found after 30-min incubation periods
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全球贸易项目编号

货号GTIN
P5172-10MG04061832785851
P5172-1MG04061834376750
P5172-5MG04061832785868