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Merck
CN

P5084

PTIO

NO activity inhibitor, powder

别名:

2-苯基-4,4,5,5-四甲基咪唑啉-1-氧代 3-氧化物

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关于此项目

经验公式(希尔记法):
C13H17N2O2
化学文摘社编号:
分子量:
233.29
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.32
MDL number:
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产品名称

PTIO,

form

powder

Quality Level

storage temp.

2-8°C

SMILES string

CC1(C)N([O])C(c2ccccc2)=[N+]([O-])C1(C)C

InChI

1S/C13H17N2O2/c1-12(2)13(3,4)15(17)11(14(12)16)10-8-6-5-7-9-10/h5-9H,1-4H3

InChI key

DYUUGILMVYJEHY-UHFFFAOYSA-N

Application

2-苯基-4,4,5,5,-四甲基咪唑啉-1-氧代 3-氧化物 (PTIO) 已被用作一氧化氮 (NO) 清除剂。

Biochem/physiol Actions

2-苯基-4, 4, 5, 5-四甲基咪唑-1-氧代 3-氧化物 (PTIOs) 衍生物与一氧化氮 (NO) 反应生成相应的的亚氨基氮氧化物 (PTIs) 和二氧化氮 (NO2)。
一种稳定的一氧化氮自由基清除剂;不影响 NO 合成酶而影响 NO;对无生物活性有显著抑制活性。
稳定的一氧化氮自由基清除剂,不影响 NO 合成酶;抑制 NO 活性。


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Ekaterina Minaeva et al.
PloS one, 12(10), e0186851-e0186851 (2017-10-20)
Truncated hemoglobins constitute a large family, present in bacteria, in archaea and in eukaryotes. However, a majority of physiological functions of these proteins remains to be elucidated. Identification and characterization of a novel role of truncated hemoglobins in the model
Victoria P A Johnstone et al.
Learning & memory (Cold Spring Harbor, N.Y.), 18(10), 625-633 (2011-09-22)
Long-term potentiation (LTP) is an important process underlying learning and memory in the brain. At CA3-CA1 synapses in the hippocampus, three discrete forms of LTP (LTP1, 2, and 3) can be differentiated on the basis of maintenance and induction mechanisms.
Luca G Mariotti et al.
International journal of radiation biology, 88(10), 751-762 (2012-06-20)
To investigate the mechanisms regulating the pathways of the bystander transmission in vitro, focusing on the radiation-perturbed signalling (via Interleukine 6, IL-6) of the irradiated cells after exposure to low doses of different radiation types. An integrated 'systems radiation biology'



全球贸易项目编号

货号GTIN
P5084-100MG04061834375807
P5084-25MG04061834375821