P4687
青霉素G 钾盐
powder, suitable for mouse embryo cell culture
别名:
苄青霉素 钾盐
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关于此项目
经验公式（希尔记法）:
C16H17KN2O4S
化学文摘社编号:
分子量:
372.48
EC Number:
204-038-0
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
3832841
MDL number:
InChI key
IYNDLOXRXUOGIU-LQDWTQKMSA-M
InChI
1S/C16H18N2O4S.K/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1
SMILES string
[K+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)Cc3ccccc3)C([O-])=O
form
powder
potency
1440-1680 units per mg
technique(s)
cell culture | embryo: suitable
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria
mode of action
cell wall synthesis | interferes
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General description
Chemical structure: β-lactam
Application
Recommended for use in embryo culture at approximaterly 100,000 units/L (60 mg/L). Solutions should be filter sterilized and stored at 2-8 °C for up to 1 week, −20 °C for extended periods. Solutions are stable at 37 °C for 3 days.
Used in cell culture in combination with streptomcyin and other antibiotics.
Biochem/physiol Actions
作用机制：青霉素G通过与青霉素结合蛋白(PBP)结合抑制肽聚糖链交联，从而抑制细胞壁合成。
抗菌谱：本品具有抗革兰氏阳性菌和革兰氏阴性菌活性。
抗菌谱：本品具有抗革兰氏阳性菌和革兰氏阴性菌活性。
Use to inhibit the synthesis of bacterial cell walls by inhibition of the cell wall peptidoglycan chain cross-lining.
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