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生物来源
Porcine stomach
类型
Grade I-S
方案
≥85% (biuret)
表单
lyophilized powder
比活
~3,000 units/mg protein (after activation to pepsin at pH 2.0 at 25°C)
纯化方式
chromatography
UniProt登记号
异质活性
pepsin, free
储存温度
2-8°C
基因信息
pig ... PGA5(396892)
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生化/生理作用
Pepsinogen is the zymogen of pepsin. It is processed by autocatalytic cleavage of 44 amino acids to generate active pepsin. Serum levels of pepsinogen have been measured to identify gastric cancer risk.
单位定义
One unit will produce a ΔA280 of 0.001 per min at pH 2.0 at 37 °C, measured as TCA-soluble products, using hemoglobin as substrate. (Final volume = 16 mL. Light path = 1 cm.)
分析说明
Protein determined by biuret.
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
Akwi W Asombang et al.
The American journal of clinical nutrition, 97(5), 1029-1035 (2013-03-29)
Gastric cancer is increasingly recognized in Zambia. Although nutritional factors contribute to gastric cancer risk, their effect in Zambia is unknown. The objective was to investigate the association between intake of dietary antioxidants, urinary 8-iso prostaglandin F2α (8-iso PGF2α) as
Kazuhiko Inoue
Nihon rinsho. Japanese journal of clinical medicine, 70(10), 1790-1794 (2012-12-04)
It is considered that Helicobacter pylori (Hp) infection is a requirement of the gastric cancer development, and that the atrophy of gastric mucosa is a high risk group of gastric cancer among Hp infected people. We can judge a super
Liying Xue et al.
Tumori, 99(2), 134-138 (2013-06-12)
The role of serum pepsinogen level and Helicobacter pylori infection in esophageal carcinoma remains controversial. It may be a risk or protective factor, or without association with esophageal carcinoma. We prospectively examined associations between serum pepsinogen status, H pylori infection
Masahira Haneda et al.
Journal of gastroenterology and hepatology, 28(1), 78-83 (2012-10-05)
Pepsinogen (PG) method is widely used to identify high risk groups of gastric cancer. It is very useful before Helicobacter pylori eradication, but after eradication the method becomes useless because the PGI, PGII, PGI/II ratios change. Therefore, we aimed to
O Szyszka et al.
Journal of animal science, 90(12), 4308-4318 (2012-06-30)
The changes in behavior associated with a (subclinical) acute and a chronic health challenge were investigated to assess their potential value for the development of an early disease detection system in beef cattle. The hypothesis was that acute challenges would
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