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Merck
CN

P4497

Sigma-Aldrich

Anti-Potassium Channel Kv1.3 (extracellular) antibody produced in rabbit

affinity isolated antibody, lyophilized powder

别名:

Anti-Voltage-gated Potassium Channel KV1.3

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About This Item

MDL编号:
UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

lyophilized powder

种属反应性

human, rat

技术

flow cytometry: 0.5-5 μg
western blot: 1:200-1:500 using rat brain membranes and human Jurkat T lymphocytes.

UniProt登记号

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... KCNA3(3738)
mouse ... Kcna3(16491)
rat ... Kcna3(29731)

免疫原

synthetic peptide corresponding to amino acid residues 211-224 of human KV1.3. The sequence has 12/14 residues identical in rat and mouse.

外形

Lyophilized from phosphate buffered saline containing 1% bovine serum albumin and 0.05% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品
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分析证书(COA)

Lot/Batch Number

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访问文档库

Andreas Schulte-Mecklenbeck et al.
European journal of immunology, 45(9), 2602-2614 (2015-07-04)
Natural killer (NK) cells are a subset of cytotoxic lymphocytes that recognize and kill tumor- and virus-infected cells without prior stimulation. Killing of target cells is a multistep process including adhesion to target cells, formation of an immunological synapse, and
Joseph Andronic et al.
Biochimica et biophysica acta, 1828(2), 699-707 (2012-10-09)
Many functions of T lymphocytes are closely related to cell volume homeostasis and regulation, which utilize a complex network of membrane channels for anions and cations. Among the various potassium channels, the voltage-gated K(V)1.3 is well known to contribute greatly
Weiwei Li et al.
Cancers, 14(11) (2022-06-11)
Pancreas ductal adenocarcinoma (PDAC) is one the most aggressive cancers and associated with very high mortality, requiring the development of novel treatments. The mitochondrial voltage-gated potassium channel, Kv1.3 is emerging as an attractive oncologic target but its function in PDAC
Stella A Nicolaou et al.
Journal of immunology (Baltimore, Md. : 1950), 183(10), 6296-6302 (2009-10-21)
The immunological synapse (IS), a highly organized structure that forms at the point of contact between a T cell and an APC, is essential for the proper development of signaling events, including the Ca(2+) response. Kv1.3 channels control Ca(2+) homeostasis

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