P4329
1,2-二棕榈酰-sn-甘油-3-磷酰胆碱
≥99% (TLC)
别名:
PC, (7R)-4-羟基-N,N,N-三甲基-10-氧代-7-[(1-氧代十六烷基)氧基]- 3,5,9-三氧杂-4-磷杂二十五烷-1-铵4-氧化物， 内盐, 1,2-二十六酰- 锡 -甘油基-3-磷酸胆碱, 1,2-二棕榈酰-sn-甘油-3-磷酰胆碱, 1,2-二棕榈酰- L -卵磷脂, 1,2-双十六酰基-sn-甘油-3-磷酰胆碱, L-α-磷脂酰胆碱，二棕榈酰, L-β,γ-二棕榈酰-α-卵磷脂, PC(16:0/16:0), 二棕榈酰磷脂酰胆碱
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所有图片(4)
About This Item
经验公式（希尔记法）:
C40H80NO8P
CAS号:
分子量:
734.04
EC 号:
MDL编号:
UNSPSC代码:
12352211
PubChem化学物质编号:
NACRES:
NA.25
推荐产品
生物来源
synthetic
质量水平
方案
≥99% (TLC)
表单
powder
官能团
phospholipid
脂质类型
phosphoglycerides
运输
ambient
储存温度
−20°C
SMILES字符串
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O
InChI
1S/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3/t38-/m1/s1
InChI key
KILNVBDSWZSGLL-KXQOOQHDSA-N
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应用
- (6)-对伞花烃钌（II）配合物对模拟癌症和健康细胞膜的Langmuir单分子膜的影响与其毒性无关。：该研究调查了钌（II）配合物与Langmuir单分子膜（包括1,2-双棕榈酰- san -甘油-3-磷酸胆碱）的相互作用，强调了癌变和健康细胞膜模型之间的行为差异（Wrobel et al., 2024）。
- 胆固醇改变模型细胞膜的界面水排列。：该研究探讨了胆固醇如何影响包括1,2-双棕榈酰-sn-甘油-3-磷酸胆碱在内的模型细胞膜界面处的水排列，为膜生物物理学提供启示（Orlikowska-Rzeznik et al., 2024）。
- 脂质组成对囊泡蛋白吸附的影响BSA案例研究。：研究了不同的脂质成分，包括1,2-双棕榈酰-sn-甘油-3-磷酸胆碱，对牛血清白蛋白在囊泡上吸附的影响，以了解蛋白质-脂质相互作用（Amarandi et al., 2024）。
- 脂筏存在时布洛芬在模型膜中的空间排列。：本文研究了布洛芬在含有脂筏和1,2-双棕榈酰-sn-甘油-3-磷酸胆碱的模型膜内的排列，揭示了药物-膜相互作用（Kashnik et al., 2024）。
联系
通过结晶纯化。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Edyta Paszko et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 48(1-2), 202-210 (2012-11-20)
Photodynamic therapy (PDT) is based on the delivery of photocytotoxic agents to a target tissue, followed by irradiation. In order to increase the efficiency of PDT in oesophageal cancer therapy, polyethylene glycol (PEG)-grafted, transferrin (Tf)-conjugated liposome formulations of 5,10,15,20-tetra(m-hydroxyphenyl)chlorin (Foscan)
Fernando R Moya et al.
Pediatrics, 115(4), 1018-1029 (2005-04-05)
Evidence suggests that synthetic surfactants consisting solely of phospholipids can be improved through the addition of peptides, such as sinapultide, that mimic the action of human surfactant protein-B (SP-B). A synthetic surfactant containing a mimic of SP-B may also reduce
Johannes Thoma et al.
Chemical communications (Cambridge, England), 48(70), 8811-8813 (2012-07-28)
We present a model system to demonstrate that the positioning of biomolecules (membrane proteins) in a nonnative, complex thin film environment can be regulated by the phase behavior of film components. Partial separation between an amphiphilic polymer and a lipid
John M Franck et al.
Journal of the American Chemical Society, 135(11), 4175-4178 (2013-01-26)
The translational hydration dynamics within 0.5-1.5 nm of the surface of a DPPC liposome, a model biomacromolecular surface, is analyzed by the recently developed Overhauser dynamic nuclear polarization (ODNP) technique. We find that dramatic changes to the bulk solvent cause
Xu Hannah Zhang et al.
Journal of cell science, 120(Pt 23), 4134-4143 (2007-11-23)
The G1 phase of the cell cycle is marked by the rapid turnover of phospholipids. This turnover is regulated by CTP:phosphocholine-cytidylyltransferase (CCT) and group VIA Ca(2+)-independent-phospholipase A(2) (iPLA(2)). We previously reported that inhibition of iPLA(2) arrests cells in G1 phase
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