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生物来源
egg yolk
质量水平
类型
Type XIII-E
检测方案
≥99% (TLC)
形式
solution
浓度
100 mg/mL in ethanol
官能团
phospholipid
脂质类型
phosphoglycerides
储存温度
−20°C
InChI
1S/C42H80NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h14,16,20-21,40H,6-13,15,17-19,22-39H2,1-5H3/b16-14-,21-20-/t40-/m1/s1
InChI key
JLPULHDHAOZNQI-ZTIMHPMXSA-N
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一般描述
磷脂酰胆碱是真核细胞中的主要膜磷脂。细胞膜的这一组分是生物活性脂质溶血磷脂酰胆碱、磷脂酸、二酰基甘油、血小板活化因子和花生四烯酸的来源。
应用
L-α-磷脂酰胆碱已用于异源物质和天然化合物的差异脂质分配实验，以测定亲脂化合物三油酸甘油酯(TG)和磷脂酰胆碱(PC)的分配系数(KTG/PC)。
生化/生理作用
磷脂酰胆碱是多种脂质信使的储备池。磷脂酰胆碱可用于制备囊泡悬浮液（通常称为脂质体）或单层脂质体。
脑磷脂脑中的主要结构磷脂，包含脂肪总量的约15%；主要局限于灰质。
警示用语：
Danger
危险声明
危险分类
Eye Irrit. 2 - Flam. Liq. 2
WGK
WGK 1
闪点(°F)
60.8 °F
闪点(°C)
16 °C
个人防护装备
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
危险化学品
Gerrit van Meer et al.
Nature reviews. Molecular cell biology, 9(2), 112-124 (2008-01-25)
Throughout the biological world, a 30 A hydrophobic film typically delimits the environments that serve as the margin between life and death for individual cells. Biochemical and biophysical findings have provided a detailed model of the composition and structure of
Wijitrapha Ruangaram et al.
Pharmaceuticals (Basel, Switzerland), 13(4) (2020-04-03)
The prevalence of obesity is increasing globally. Despite the availability of a variety of anti-obesogenic drugs, including therapies under clinical development, these treatments are often indicated for patients with severe obesity, making them unsuitable for patients with mild obesity or
Takeshi Harayama et al.
Journal of lipid research, 50(9), 1824-1831 (2009-04-23)
Pulmonary surfactant is a complex of phospholipids and proteins lining the alveolar walls of the lung. It reduces surface tension in the alveoli, and is critical for normal respiration. Pulmonary surfactant phospholipids consist mainly of phosphatidylcholine (PC) and phosphatidylglycerol (PG).
A review on phospholipids and their main applications in drug delivery systems
Li J, et al.
Asian Journal of Pharmaceutical Sciences , 10, 81-98 (2015)
Heinrich Sandermann
FEBS letters, 554(1-2), 165-168 (2003-11-05)
Octanol-1/water partitioning currently provides the most widely used model system to simulate both phospholipid target lipids and triglyceride storage lipids. A differentiation between the two lipid classes is now achieved by making use of a water-induced lipid phase separation. Coefficients
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