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应用
聚肌苷酸（聚（I））是一种肌苷的均聚物，其可与聚胞苷酸（聚（C））一起形成双链均聚物（聚（I）·聚（C））。 TLR3 识别双链 RNA，并且是针对病毒病原体的免疫应答的主要效应分子。（Poly（I）•Poly（C））被用作研究 TLR3 水平的细胞信号传导的模型 RNA。Poly（IC）是一种 TRIF 依赖性 toll 样受体-3（TLR3）配体。
制备说明
通过多核苷酸磷酸化酶法从 IDP 制备。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
从最新的版本中选择一种：
分析证书(COA)
Lot/Batch Number
Overlapping and distinct roles of GRK5 in TLR2-, and TLR3-induced inflammatory response in vivo.
Packiriswamy N, Parvataneni S, Parameswaran N.
Cellular Immunology, 107-111 (2011)
Gennady Dvoryanchikov et al.
Nature communications, 8(1), 760-760 (2017-10-04)
Taste buds are innervated by neurons whose cell bodies reside in cranial sensory ganglia. Studies on the functional properties and connectivity of these neurons are hindered by the lack of markers to define their molecular identities and classes. The mouse
Xingbo Wang et al.
Veterinary microbiology, 251, 108895-108895 (2020-10-31)
RNA binding ability and cellular distribution are important for nonstructural protein 1 (NS1) of influenza A virus to act as a viral regulatory factor to control virus life cycle. In this study, we identified that the N-terminal residues 19-21 of
Caiqi Ma et al.
International journal of oncology, 54(2), 572-584 (2018-11-30)
Gastric cancer is one of the most malignant tumor types, and its metastasis is a notable cause of mortality. Among the methods of tumor metastasis, lymphatic metastasis is the predominant one in gastric cancer. A previous study reported that the
Activation of chemokine and inflammatory cytokine response in HCV-infected hepatocytes depends on TLR3 sensing of HCV dsRNA intermediates.
Li K, Li NL, Wei D, Pfeffer SR, et al.
Hepatology, 55(3), 666-675 (2011)
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