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质量水平
检测方案
≥98% (HPLC)
形式
solid
储存条件
desiccated
protect from light
under inert gas
颜色
off-white
溶解性
DMSO: >5 mg/mL
H2O: insoluble
储存温度
2-8°C
SMILES字符串
Cl[H].Cc1cc(O)c(C)c2sc(N)nc12
InChI
1S/C9H10N2OS.ClH/c1-4-3-6(12)5(2)8-7(4)11-9(10)13-8;/h3,12H,1-2H3,(H2,10,11);1H
InChI key
AIOZIUZKTGVUHB-UHFFFAOYSA-N
生化/生理作用
Cell-permeable polyglutamine aggregation inhibitor
警示用语:
Warning
危险分类
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
新产品
Proceedings of the National Academy of Sciences of the United States of America, 99 Suppl 4, 16400-16406 (2002-08-30)
Preventing the formation of insoluble polyglutamine containing protein aggregates in neurons may represent an attractive therapeutic strategy to ameliorate Huntington's disease (HD). Therefore, the ability to screen for small molecules that suppress the self-assembly of huntingtin would have potential clinical
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