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Merck
CN

P3761

Sigma-Aldrich

戊巴比妥 钠盐

别名:

5-乙基-5-(1-甲基丁基)-2,4,6-三氧六氢嘧啶, 戊巴比妥

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About This Item

经验公式(希尔记法):
C11H17N2NaO3
CAS号:
分子量:
248.25
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:

表单

powder

质量水平

药品控制

USDEA Schedule II; Home Office Schedule 3; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada

溶解性

H2O: soluble
alcohol: soluble

SMILES字符串

[Na].CCCC(C)C1(CC)C(=O)NC(=O)NC1=O

InChI

1S/C11H18N2O3.Na.H/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15;;/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16);;

InChI key

PGOYUXGHADTNIB-UHFFFAOYSA-N

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应用

戊巴比妥钠盐在各种体外研究之前被用作大鼠和小鼠的麻醉剂。

生化/生理作用

戊巴比妥(PB)是一种巴比妥酸盐,是γ-氨基丁酸亚型A (GABAA)受体的配体。它是一种镇静麻醉剂,主要用于啮齿动物安乐死。戊巴比妥具有催眠功能和放松肌肉的特性。它能增强氨基丁酸能活性。腹腔注射PB可导致右立反射(LORR)丧失和心跳停止。

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险声明

危险分类

Acute Tox. 3 Oral - Repr. 2 - STOT SE 3

靶器官

Central nervous system

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How can I solubilize Pentobarbital sodium salt, Product P3761?

    This product is soluble in water (50 mg/ml), with heat and sonication as needed, yielding a clear to slightly hazy, colorless solution.

  4. How can I store my solution of Pentobarbital sodium salt, Product P3761?

    Solutions of the sodium salt are typically pH 9.0 - 11.0 (BP/USP). If the pH is lowered, the free acid will precipitate from solution. Solutions decompose on standing, the decomposition being accelerated at higher temperatures.  We recommend to make solutions fresh.

  5. Is Pentobarbital sodium salt available as a solution?

    We do not offer a solution of pentobarbital as it is not stable as a solution.

  6. What is the shelf life for Pentobarbital sodium salt, Product P3761?

    Product No. P3761 has a retest date of 3 years from date of manufacture.  

  7. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  8. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  9. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

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