P3635
5β-Pregnane-3α,20α-diol glucuronide
≥98.00% (TLC), powder, progesterone metabolite
别名:
P3G, PDG, Pn3-G, Pregnanediol-3a-glucuronide, Pregnanediol-glucuronide, 3α,20α-Dihydroxy-5β-pregnane 3-glucuronide
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所有图片(1)
About This Item
经验公式（希尔记法）:
C27H44O8
CAS号:
分子量:
496.63
MDL编号:
UNSPSC代码:
51111800
PubChem化学物质编号:
NACRES:
NA.77
推荐产品
产品名称
5β-Pregnane-3α,20α-diol glucuronide,
无菌性
non-sterile
方案
≥98.00% (TLC)
表单
powder
技术
enzyme immunoassay: suitable
溶解性
ethanol: 20 mg/mL, clear, colorless
运输
ambient
储存温度
−20°C
SMILES字符串
CC(O)C1CCC2C3CCC4CC(CCC4(C)C3CCC12C)OC5OC(C(O)C(O)C5O)C(O)=O
InChI
1S/C27H44O8/c1-13(28)17-6-7-18-16-5-4-14-12-15(8-10-26(14,2)19(16)9-11-27(17,18)3)34-25-22(31)20(29)21(30)23(35-25)24(32)33/h13-23,25,28-31H,4-12H2,1-3H3,(H,32,33)
InChI key
ZFFFJLDTCLJDHL-UHFFFAOYSA-N
一般描述
5β-Pregnane-3α,20α-diol glucuronide is a progesterone metabolite predominant in urine, during pregnancy. Presence of 5β-Pregnane-3α,20α-diol glucuronide in the urine indicates pregnancy, but it might also account for pseudopregnancy. It is useful in predicting the delivery time/end of pseudopregnancy.
Urinary pregnanediol glucuronide (PdG) seems to serve as an effective clinical marker for monitoring progesterone supplementation. PdG, along with other urinary metabolites such as luteinizing hormone (LH), follicle stimulating hormone (FSH), and estrone glucuronide (ElG), exhibit a strong association with ovarian excretion rates and demonstrate a high correlation with serum reproductive hormones. As a result, they can be used interchangeably to effectively monitor ovarian steroidogenesis.
应用
5β-Pregnane-3α,20α-diol glucuronide has been used in a cross-sectional analysis of hormone levels. It has also been used as a standard to measure estradiol-17β, pregnanediol-glucuronide (PdG) by a double-antibody enzyme immunoassay.
5β-Pregnane-3α,20α-diol glucuronide has been used in steroid enzyme immunoassay.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
监管及禁止进口产品
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Meena P Desai et al.
Journal of clinical laboratory analysis, 21(2), 55-60 (2007-03-28)
This study characterizes age-related changes in bone turnover markers in relation to ovarian hormones. The data (N = 236) were divided into 5-year age bands and three groups: premenopausal (Group I, N = 139), perimenopausal (Group II, N = 30)
Dana Rochester et al.
Fertility and sterility, 92(4), 1410-1415 (2008-10-03)
To determine whether obesity-related reproductive endocrine abnormalities in ovulatory women are reversible with weight loss. Observational cohort study. Healthy volunteers in an academic research environment. Women aged 18-48 years with regular menstrual cycles 21-40 days and a body mass index
Robert W Shumaker et al.
Interdisciplinary topics in gerontology, 36, 147-161 (2008-06-05)
Data from wild populations demonstrate that orangutans have the slowest life history of all the great apes. In this chapter, we provide an overview of reproduction and life history traits of female orangutans in the wild and captivity. This comparison
N Santoro et al.
The Journal of clinical endocrinology and metabolism, 93(5), 1711-1721 (2008-02-21)
Reproductive hormones are incompletely characterized during the menopause transition (MT). Increased anovulation and decreased progesterone accompany progress through the MT. The Daily Hormone Study (DHS) of the Study of Women's Health Across the Nation (SWAN) included 848 women aged 43-53
Longitudinal fecal hormone analysis for monitoring reproductive activity in the female polar bear (Ursus maritimus)
Stoops MA, et al.
Theriogenology, 78(9), 1977-1986 (2012)
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