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Merck
CN
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文件

安全信息

P3168

Sigma-Aldrich

植酸 十二钠盐 水合物

≥90%, from rice

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别名:
Inositol hexakisphosphate, InsP6, 肌醇六(磷酸二氢酯)
经验公式（希尔记法）:
C6H6Na12O24P6 · xH2O
CAS号:
123408-98-0
分子量:
923.82 (anhydrous basis)
MDL编号:
MFCD00149213
UNSPSC代码:
12352201

生物来源

rice

检测方案

≥90%

SMILES字符串

[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[H]O[H].[O-]P([O-])(=O)O[C@H]1[C@H](OP([O-])([O-])=O)[C@H](OP([O-])([O-])=O)[C@H](OP([O-])([O-])=O)[C@@H](OP([O-])([O-])=O)[C@@H]1OP([O-])([O-])=O

生化/生理作用

Phytic acid is present in all eukaryotic cells. In plants, it is known to function as a [PO4]3− storage depot and precursor for other inositol phosphates and pyrophosphates. Its high surface negative charge makes it a potent chelator of divalent and trivalent cations in vitro, and it is most likely associated with Ca2+ or Mg2+ ions in vivo. In yeast, phytic acid acts with the nuclear pore protein Gle1 to regulate the nuclear export of mRNA by coactivating the RNA-dependent ATPase activity of DExD-box protein 5 (Dbp5).

质量

Contains minute amounts of black particles.

法规信息

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Andreia Biolo et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(6), 1926-1929 (2009-02-11)
A major determinant of maximal exercise capacity is the delivery of oxygen to exercising muscles. myo-Inositol trispyrophosphate (ITPP) is a recently identified membrane-permeant molecule that causes allosteric regulation of Hb oxygen binding affinity. In normal mice, i.p. administration of ITPP

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