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Merck
CN
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安全信息

P3115

Sigma-Aldrich

Protein Kinase C Inhibitor, Myristoylated

≥7.5 mg/mL (peptide and counter ion), ≥95% (Minimum peptide content 70%, HPLC), aqueous solution (neutral pH)

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别名:
Myr-Arg-Phe-Ala-Arg-Lys-Gly-Ala-Leu-Arg-Gln-Lys-Asn-Val, Myr-RFARKGALRQKNV
MDL编号:
MFCD01635303
UNSPSC代码:
12352200
NACRES:
NA.77

生物来源

synthetic (organic
organic)

检测方案

≥95% (Minimum peptide content 70%, HPLC)

形式

aqueous solution (neutral pH)

分子量

1,754.3 Da (Fast Atomic Bombardment Mass Spectrometry)
 1.75 kDa

组成

Peptide content, ≥70%

浓度

≥7.5 mg/mL (peptide and counter ion)

运输

dry ice

储存温度

−20°C

应用

Protein Kinase C (PKC) Inhibitor, Myristoylated is supplied ready for use in kinase reactions. An inhibitor peptide (concentration of 50 to 100 μM) is recommended, depending on the concentration of PKC and the duration of the incubation.

生化/生理作用

Protein Kinase C Inhibitor, Myristoylated is a cell permeable, specific inhibitor of calcium and phospholipid-dependent Protein Kinase C.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

常规特殊物品

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T Eichholtz et al.
The Journal of biological chemistry, 268(3), 1982-1986 (1993-01-25)
Synthetic peptides corresponding to the pseudosubstrate domains of protein kinase C (PKC) have been used as specific inhibitors of PKC in in vitro assays and permeabilized cell systems. However, their use in vivo was hampered by the impermeability of the
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