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经验公式(希尔记法):
C36H72NO8P
化学文摘社编号:
分子量:
677.93
UNSPSC Code:
12352211
NACRES:
NA.77
PubChem Substance ID:
EC Number:
242-085-9
Beilstein/REAXYS Number:
3921768
MDL number:
产品名称
1,2-二肉豆蔻酰基-sn-甘油-3-磷酸胆碱, ≥99%
InChI key
CITHEXJVPOWHKC-UUWRZZSWSA-N
InChI
1S/C36H72NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-35(38)42-32-34(33-44-46(40,41)43-31-30-37(3,4)5)45-36(39)29-27-25-23-21-19-17-15-13-11-9-7-2/h34H,6-33H2,1-5H3/t34-/m1/s1
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O)=O
assay
≥99%
form
powder
lipid type
phosphoglycerides
storage temp.
−20°C
Quality Level
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Application
1,2-二肉豆蔻酰-sn-丙三基-3-胆碱磷酸已用作标准品,通过 LC-ESI-MS 进行磷脂分析。
Biochem/physiol Actions
1,2-二肉豆蔻酰-sn-丙三基-3-胆碱磷酸 (DMPC) 具有增强卡莫氟稳定性和体外抗增殖作用的能力。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
1, 2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) increases Carmofur stability and in vitro antiproliferative effect
Domracheva I, et al.
Toxicology Reports, 2, 377-383 (2015)
Assessment of the effects of hydrocarbon contamination on the sedimentary bacterial communities and determination of the polar lipid fraction purity: relevance of intact phospholipid analysis
Mazzella N, et al.
Marine Chemistry, 103(3-4), 304-317 (2007)
Brian S Vad et al.
The Journal of membrane biology, 248(3), 487-496 (2015-03-25)
The biological activity of antimicrobial peptides is believed to be closely linked to their ability to perturb bacterial membranes. This makes it important to understand the basis of their membrane-binding properties. Here, we present a biophysical analysis of the interactions
Sevim Ozgur et al.
Molecular and cellular biology, 30(17), 4308-4323 (2010-06-30)
In eukaryotic cells, degradation of many mRNAs is initiated by removal of the poly(A) tail followed by decapping and 5'-3' exonucleolytic decay. Although the order of these events is well established, we are still lacking a mechanistic understanding of how
Liyang Cui et al.
ACS nano, 9(4), 4484-4495 (2015-04-02)
PEGylation (PEG) is the most commonly adopted strategy to prolong nanoparticles' vascular circulation by mitigating the reticuloendothelial system uptake. However, there remain many concerns in regards to its immunogenicity, targeting efficiency, etc., which inspires pursuit of alternate, non-PEGylated systems. We
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