推荐产品
表单
powder
质量水平
药品控制
USDEA Schedule I; Home Office Schedule 1; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal)
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
forensics and toxicology
pharmaceutical (small molecule)
veterinary
储存温度
−20°C
SMILES字符串
CN(C)CCc1c[nH]c2cccc(O)c12
InChI
1S/C12H16N2O/c1-14(2)7-6-9-8-13-10-4-3-5-11(15)12(9)10/h3-5,8,13,15H,6-7H2,1-2H3
InChI key
SPCIYGNTAMCTRO-UHFFFAOYSA-N
基因信息
human ... HTR1A(3350)
rat ... Htr2a(29595) , Htr2c(25187)
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生化/生理作用
Hallucinogen originally isolated from the mushroom, Psilocybe mexicana, non-selective serotonin receptor agonist.
Hallucinogen; non-selective serotonin receptor agonist.
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Howard Sard et al.
Bioorganic & medicinal chemistry letters, 15(20), 4555-4559 (2005-08-03)
An SAR study of psilocybin and psilocin derivatives reveals that 1-methylpsilocin is a selective agonist at the h5-HT(2C) receptor. The corresponding phosphate derivative, 1-methylpsilocybin, shows efficacy in an animal model for obsessive-compulsive disorder, as does 4-fluoro-N,N-dimethyltryptamine. These results suggest a
N Almaula et al.
Molecular pharmacology, 50(1), 34-42 (1996-07-01)
An important determinant of the neurobehavioral responses induced by a drug is its relative receptor selectivity. The molecular basis of ligand selectivity of hallucinogenic and nonhallucinogenic compounds of varying structural classes for the human 5-hydroxytryptamine (5-HT)2A and 5-HT2C receptors was
N Milne et al.
Metabolic engineering, 60, 25-36 (2020-04-01)
Psilocybin is a tryptamine-derived psychoactive alkaloid found mainly in the fungal genus Psilocybe, among others, and is the active ingredient in so-called "magic mushrooms". Although its notoriety originates from its psychotropic properties and popular use as a recreational drug, clinical
Thomas Keller et al.
Forensic science international, 161(2-3), 130-140 (2006-07-13)
Ion mobility spectrometry (IMS) has been known as an analytical technique since the late 1960s and early 1970s. To date, it has been successfully utilized for the detection of environmental pollutants, warfare agents, explosives, herbicides, pesticides, petroleum products as well
Michael Beuhler et al.
Annals of emergency medicine, 44(2), 114-120 (2004-07-28)
The Meixner test has been suggested to identify the presence of alpha-amanitin, one of the toxic compounds in Amanita mushrooms. We attempted to determine the detection limit of the Meixner test for alpha-amanitin and to determine the percentage of positive
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