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Merck
CN

P2153

Sigma-Aldrich

Phenylacetyl coenzyme A lithium salt

~95%

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About This Item

经验公式(希尔记法):
C29H42N7O17P3S
分子量:
885.67
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.51

方案

~95%

质量水平

表单

powder

储存温度

−20°C

SMILES字符串

[Li].CC(C)(COP(O)(=O)OP(O)(=O)OCC1OC(C(O)C1OP(O)(O)=O)n2cnc3c(N)ncnc23)C(O)C(=O)NCCC(=O)NCCSC(=O)Cc4ccccc4

InChI

1S/C29H42N7O17P3S.Li.H/c1-29(2,24(40)27(41)32-9-8-19(37)31-10-11-57-20(38)12-17-6-4-3-5-7-17)14-50-56(47,48)53-55(45,46)49-13-18-23(52-54(42,43)44)22(39)28(51-18)36-16-35-21-25(30)33-15-34-26(21)36;;/h3-7,15-16,18,22-24,28,39-40H,8-14H2,1-2H3,(H,31,37)(H,32,41)(H,45,46)(H,47,48)(H2,30,33,34)(H2,42,43,44);;

InChI key

BYSZOQQABOXIQX-UHFFFAOYSA-N

应用

Coenzyme A functions as an acyl group carrier, acetyl-CoA. Phenylacetyl coenzyme A (Phenylacetyl-CoA) is used to study the mechanism of action of the TetR family transcriptional repressor PaaR. Phenylacetyl-CoA is used to study the phenylacetyl-CoA monooxygenase complex found in bacteria such as E. coli.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

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Juan L Ramos et al.
Microbiology and molecular biology reviews : MMBR, 69(2), 326-356 (2005-06-10)
We have developed a general profile for the proteins of the TetR family of repressors. The stretch that best defines the profile of this family is made up of 47 amino acid residues that correspond to the helix-turn-helix DNA binding
Teresa del Peso-Santos et al.
Molecular microbiology, 69(2), 317-330 (2008-06-12)
Pseudomonas sp. strain Y2 degrades styrene through oxidation to phenylacetic acid via the styABCD operon-encoded enzymes, whose expression is induced in response to styrene by the StyS/StyR two-component regulatory system. Further transformation of phenylacetic acid to tricarboxylic acid cycle intermediates
Andrey M Grishin et al.
Acta crystallographica. Section F, Structural biology and crystallization communications, 66(Pt 9), 1045-1049 (2010-09-09)
The Escherichia coli paa operon encodes enzymes of the phenylacetic acid-utilization pathway that metabolizes phenylacetate in the form of a coenzyme A (CoA) derivative. The phenylacetyl-coenzyme A oxygenase complex, which has been postulated to contain five components designated PaaABCDE, catalyzes
Andrey M Grishin et al.
The Journal of biological chemistry, 286(12), 10735-10743 (2011-01-21)
The utilization of phenylacetic acid (PA) in Escherichia coli occurs through a hybrid pathway that shows features of both aerobic and anaerobic metabolism. Oxygenation of the aromatic ring is performed by a multisubunit phenylacetyl-coenzyme A oxygenase complex that shares remote
Keiko Sakamoto et al.
Journal of bacteriology, 193(17), 4388-4395 (2011-07-05)
Phenylacetic acid (PAA) is a common intermediate in the catabolic pathways of several structurally related aromatic compounds. It is converted into phenylacetyl coenzyme A (PA-CoA), which is degraded to general metabolites by a set of enzymes. Within the genome of

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