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生物来源
bovine brain
质量水平
方案
>90% (SDS-GE)
表单
buffered aqueous glycerol solution
比活
~1000 units/mg protein
分子量
42-45 kDa
包装
vial of 1 μg
技术
ligand binding assay: suitable
UniProt登记号
运输
dry ice
储存温度
−70°C
基因信息
bovine ... PPP2CA(282320)
一般描述
Protein phosphatase 2C (PP2C) is a member of protein phosphatases, Mg2+/Mn2+ dependent (PPM) family. PP2C is a monomeric enzymes found in both prokaryotes and eukaryotes.
生化/生理作用
In Arabidopsis, protein phosphatase 2C (PP2C) negatively regulates plant hormone, abscisic acid (ABA) signal transduction. In eukaryotes, this protein modulates the cell cycle by reversing the activating phosphorylation of cyclin-dependent protein kinases (CDKs). PP2C acts as a crucial physiological regulators of cell growth and of cellular stress signaling.
单位定义
One unit will release 1.0 nanomole of phosphate from 32P-labeled myelin basic protein at pH 7.0 at 30 °C
外形
Solution in 50 mM Tris-HCl, pH 7.0, containing 14 mM 2-mercaptoethanol, 1 mM benzamidine, 0.1 mM PMSF, 1 mM EDTA, and 50% glycerol
警示用语：
Warning
危险声明
危险分类
Skin Sens. 1
储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
动植物源性产品
Role of type 2C protein phosphatases in growth regulation and in cellular stress signaling.
Lammers T and Lavi S
Critical Reviews in Biochemistry and Molecular Biology, 42, 437-461 (2007)
ABI1 Protein Phosphatase 2C Is a Negative Regulator of Abscisic Acid Signaling
Gosti F, et al.
Plant Cell, 11, 1897-1910 (1999)
A protein phosphatase 2C involved in ABA signal transduction in Arabidopsis thaliana
Meyer K, et al.
Science, 264, 1452-1455 (1994)
Plant PP2C phosphatases: emerging functions in stress signaling.
Schweighofer A, et al.
Trends in Plant Science, 9, 236-243 (2004)
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