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Merck
CN
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文件

安全信息

P1527

Sigma-Aldrich

1,2-Di-O-hexadecyl-sn-glycero-3-phosphocholine

≥99% (TLC)

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别名:
(7R)-7-(Hexadecyloxy)-4-hydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphapentacosan-1-aminium 4-oxide, inner salt, 1-Hexadecyl-2-hexadecyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, 1,2-dihexadecyl, L-α-Lecithin dihexadecyl ether, L-α-Phosphatidylcholine, di-O-hexadecyl, L-β,γ-Dihexadecyl-α-lecithin, DCPC, Glycerol-3-sn-phosphorylcholine 1,2-bis(hexadecyl ether), PC(O-16:0/O-16:0)
经验公式（希尔记法）:
C40H84NO6P
CAS号:
36314-47-3
分子量:
706.07
Beilstein:
4168071
EC 号:
252-968-0
MDL编号:
MFCD00066564
UNSPSC代码:
12352211
PubChem化学物质编号:
24898214
NACRES:
NA.25

检测方案

≥99% (TLC)

形式

powder

官能团

phospholipid

脂质类型

phosphoglycerides

运输

ambient

储存温度

−20°C

SMILES字符串

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OCCCCCCCCCCCCCCCC)COCCCCCCCCCCCCCCCC)=O

InChI

1S/C40H85NO6P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-35-44-38-40(39-47-48(42,43)46-37-34-41(3,4)5)45-36-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h40H,6-39H2,1-5H3,(H,42,43)

InChI key

DACAUPQETXAEBT-UHFFFAOYSA-N

应用

1,2-Di-O-hexadecyl-sn-glycero-3-phosphocholine (DHPC) may be suitable for use in coating hydrophobic styrene-divinylbenzene. It may also be suitable for spreading onto the subphase to form monolayer to perform penetration studies of phospholipase A2 (PLA2).

生化/生理作用

1,2-Di-O-hexadecyl-sn-glycero-3-phosphocholine (DHPC) is a nonhydrolyzable ether analog of phosphocholine.

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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Maria Oranges et al.
Chemistry and physics of lipids, 212, 130-137 (2018-02-08)
Electron spin echo envelope modulation (ESEEM) and conventional electron paramagnetic resonance (EPR) of site-specifically spin-labelled phospholipids are used to investigate the effect of ether-linked chains on the water-penetration and polarity profiles, as well as the phase behaviour and chain flexibility
Roles of Trp31 in high membrane binding and proinflammatory activity of human group V phospholipase A2
Han SK, et al.
The Journal of biological chemistry, 274(17), 11881-11888 (1999)
A Structure-Function Study of the C2 Domain of Cytosolic Phospholipase A2 IDENTIFICATION OF ESSENTIAL CALCIUM LIGANDS AND HYDROPHOBIC MEMBRANE BINDING RESIDUES
Bittova L, et al.
The Journal of biological chemistry, 274(14), 9665-9672 (1999)

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