P1378
邻苯二甲醛
≥97% (HPLC), powder or crystals
别名:
1,2-苯二甲醛, OPA, 邻苯二醛, 酞醛
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关于此项目
经验公式（希尔记法）:
C8H6O2
化学文摘社编号:
分子量:
134.13
UNSPSC Code:
12352201
NACRES:
NA.21
PubChem Substance ID:
EC Number:
211-402-2
Beilstein/REAXYS Number:
878317
MDL number:
Assay:
≥97% (HPLC)
Form:
powder or crystals
InChI key
ZWLUXSQADUDCSB-UHFFFAOYSA-N
InChI
1S/C8H6O2/c9-5-7-3-1-2-4-8(7)6-10/h1-6H
SMILES string
O=Cc1ccccc1C=O
assay
≥97% (HPLC)
form
powder or crystals
color
white to light yellow
mp
55-58 °C
storage temp.
2-8°C
Quality Level
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Application
苯二醛已用于：
- 采用终点荧光敏感检测的分光光度法检测精氨酸
- 试剂流与样品一起产生荧光产物，以测定海水中的氨含量
- 邻苯二醛分光光度测定（OPA测试），以测定菌株和商用培养物的蛋白水解活性（PA）
Biochem/physiol Actions
邻苯二醛（OPA）可在与氨基酸反应时形成荧光衍生物。
苯二醛可用于高效液相色谱（HPLC）分离的氨基酸柱前衍生化。还可用于蛋白质巯基的流式细胞术测定。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
269.6 °F - closed cup
flash_point_c
132 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Niklas Krause et al.
Scandinavian journal of work, environment & health, 41(2), 124-139 (2015-01-20)
This study aimed to assess the effects of physically demanding work - measured as energy expenditure (EE) during occupational physical activities (OPA) - on risk of acute myocardial infarction (AMI) among men with and without preexisting ischemic heart disease (IHD).
Bianca de Moraes Fracasso et al.
PloS one, 14(1), e0209964-e0209964 (2019-01-12)
Circulating advanced glycation end products (AGE) and their receptor, RAGE, are increased after a myocardial infarction (MI) episode and seem to be associated with worse prognosis in patients. Despite the increasing importance of these molecules in the course of cardiac
I Molnár-Perl
Journal of chromatography. A, 913(1-2), 283-302 (2001-05-18)
An overview is presented of HPLC methods currently in use to determine amino acids as their o-phthaldialdyde derivatives in the presence of various SH-group-containing additives. Crucial points that proved to influence the stability of the amino acid OPA derivatives have
Yi-Jhen Lai et al.
Talanta, 91, 103-109 (2012-03-01)
This study reports a selective and sensitive method for fluorescent detection of total, protein-bound, free, and free oxidized homocysteine (HCys) using tris(2-carboxyethyl)phosphine (TCEP) as a reducing agent, fluorosurfactant-capped gold nanoparticles (FSN-AuNP) as a preconcentrating probe, and o-phthaldialdehyde (OPA) as a
Chao Che et al.
ACS combinatorial science, 15(4), 202-207 (2013-02-28)
One-pot and efficient syntheses of structurally diverse isoquinolin-3-ones and isoquinolin-3-one-based benzo-1,4-diazepin-2,5-diones have been developed. The notable features of the process include the Ugi condensation of monomasked phthalaldehydes with amines, carboxylic acids, and isonitriles, followed by HClO4-mediated intramolecular condensation of the
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