Amino Acid Sequence
Tyr-Pro-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-NH2
一般描述
Human peptide YY (PYY) is secreted by mucosal L cells in the distal ileum, colon and rectum. It consists of 36 amino acids. The gene encoding PYY is localized on human chromosome 17q21.1.
应用
Peptide YY human has been used as a supplement in Roswell Park Memorial Institute medium (RPMI medium) to culture pancreatic duct-derived cells.
生化/生理作用
Gut hormone that inhibits both secretin and cholecystokinin-stimulated pancreatic secretion. Endogenous nonselective agonist at NPY receptors.
Human peptide YY (PYY) has a role in food ingestion, gut motility and insulin secretion. The protein suppresses appetite. It has been associated with obesity and type 2 diabetes. PYY also has a role in energy homeostasis.
其他说明
Lyophilized from 0.1% TFA in H2O
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
监管及禁止进口产品
Genomic and gene expression signature of the pre-invasive
testicular carcinoma in situ
testicular carcinoma in situ
Kristian Almstrup
Cell and Tissue Research (2005)
TLR ligands and butyrate increase Pyy expression through two distinct but inter-regulated pathways.
Larraufie P
Cellular Microbiology (2017)
Rapid and Efficient In Vitro Generation of Pancreatic Islet
Progenitor Cells from Nonendocrine Epithelial Cells in the
Adult Human Pancreas
Progenitor Cells from Nonendocrine Epithelial Cells in the
Adult Human Pancreas
JOSEPHINE S. D?ALESSANDRO
Stem Cells and Development (2007)
Expression of peptide YY by human blood leukocytes.
Holler JP
Peptides (2014)
The Association of Serum Total Peptide YY (PYY) with Obesity and Body Fat Measures in the CODING Study.
Cahill F
PLoS ONE (2014)
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