P1138
1,2-二硬脂酰- 锡 -甘油基-3-磷酸胆碱
≥99%
别名:
PC, 3- sn -磷脂酰胆碱，1,2-二硬脂酰, L-α-磷脂酰胆碱，二硬脂酰, L-β,γ-二硬脂酰-α-卵磷脂, DSPC, PC(18:0/18:0)
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关于此项目
经验公式（希尔记法）:
C44H88NO8P
化学文摘社编号:
分子量:
790.15
UNSPSC Code:
12352211
NACRES:
NA.25
PubChem Substance ID:
EC Number:
212-440-2
Beilstein/REAXYS Number:
3923978
MDL number:
产品名称
1,2-二硬脂酰- 锡 -甘油基-3-磷酸胆碱, ≥99%
InChI key
NRJAVPSFFCBXDT-HUESYALOSA-N
InChI
1S/C44H88NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h42H,6-41H2,1-5H3/t42-/m1/s1
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O
biological source
semisynthetic
assay
≥99%
form
powder
functional group
phospholipid
lipid type
phosphoglycerides
shipped in
ambient
storage temp.
−20°C
Quality Level
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Application
- 金刚烷胺与相分离脂质膜的相互作用研究。：该研究探讨了金刚烷胺与相分离脂质膜之间的相互作用，深入了解了1,2-二硬脂酰-sn-甘油-3-磷酸胆碱在膜结构和功能中的作用（Kinnun et al., 2024）。
- 采用微流控涂层技术设计电荷转换脂质纳米颗粒。：该研究使用1,2-二硬脂酰-sn-甘油-3-磷酸胆碱设计了具有电荷转换能力的脂质纳米颗粒，优化了药物递送系统（Zöller et al., 2024）。
- 主动和被动包封法将蛋白质装载到脂质体中的研究和比较。：该研究比较了使用1,2-二硬脂酰-sn-甘油-3-磷酸胆碱将蛋白质包封到脂质体中的方法，推动了药物递送技术的发展（Pisani et al., 2023）。
General description
通过单一水合步骤形成负载有所选分子的无热原的，成分明确的脂质体。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Proceedings of the National Academy of Sciences of the United States of America, 110(16), 6512-6517 (2013-03-29)
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Pan Li et al.
Journal of controlled release : official journal of the Controlled Release Society, 162(2), 349-354 (2012-07-18)
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Antonella Accardo et al.
International journal of nanomedicine, 7, 2007-2017 (2012-05-24)
Drug delivery systems consisting of liposomes displaying a cell surface receptor-targeting peptide are being developed to specifically deliver chemotherapeutic drugs to tumors overexpressing a target receptor. This study addresses novel liposome composition approaches to specifically target tissues overexpressing bombesin (BN)
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Journal of controlled release : official journal of the Controlled Release Society, 162(2), 330-339 (2012-07-18)
Nanoparticulate drug carriers such as liposomal drug delivery systems are of considerable interest in cancer therapy because of their ability to passively accumulate in solid tumors. For liposomes to have practical utility for antitumor therapy in patients, however, optimization of
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