推荐产品
生物来源
semisynthetic
质量水平
方案
≥99%
表单
powder
官能团
phospholipid
脂质类型
phosphoglycerides
运输
ambient
储存温度
−20°C
SMILES字符串
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O
InChI
1S/C44H88NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h42H,6-41H2,1-5H3/t42-/m1/s1
InChI key
NRJAVPSFFCBXDT-HUESYALOSA-N
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一般描述
通过单一水合步骤形成负载有所选分子的无热原的，成分明确的脂质体。
应用
- 金刚烷胺与相分离脂质膜的相互作用研究。：该研究探讨了金刚烷胺与相分离脂质膜之间的相互作用，深入了解了1,2-二硬脂酰-sn-甘油-3-磷酸胆碱在膜结构和功能中的作用（Kinnun et al., 2024）。
- 采用微流控涂层技术设计电荷转换脂质纳米颗粒。：该研究使用1,2-二硬脂酰-sn-甘油-3-磷酸胆碱设计了具有电荷转换能力的脂质纳米颗粒，优化了药物递送系统（Zöller et al., 2024）。
- 主动和被动包封法将蛋白质装载到脂质体中的研究和比较。：该研究比较了使用1,2-二硬脂酰-sn-甘油-3-磷酸胆碱将蛋白质包封到脂质体中的方法，推动了药物递送技术的发展（Pisani et al., 2023）。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Peter J Kueffer et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(16), 6512-6517 (2013-03-29)
The application of boron neutron capture therapy (BNCT) following liposomal delivery of a (10)B-enriched polyhedral borane and a carborane against mouse mammary adenocarcinoma solid tumors was investigated. Unilamellar liposomes with a mean diameter of 134 nm or less, composed of
Pan Li et al.
Journal of controlled release : official journal of the Controlled Release Society, 162(2), 349-354 (2012-07-18)
Ultrasound targeted microbubble destruction (UTMD) was one of the most promising strategies to enhance drug delivery in cancer therapy. Microbubbles (MBs) serve as a vehicle to carry anti-tumor drugs and locally release them when exposed to therapeutic ultrasound, resulting in
Sweta Modi et al.
Journal of controlled release : official journal of the Controlled Release Society, 162(2), 330-339 (2012-07-18)
Nanoparticulate drug carriers such as liposomal drug delivery systems are of considerable interest in cancer therapy because of their ability to passively accumulate in solid tumors. For liposomes to have practical utility for antitumor therapy in patients, however, optimization of
Mette Marie Bruun Nielsen et al.
Langmuir : the ACS journal of surfaces and colloids, 29(5), 1525-1532 (2013-01-04)
Imaging ellipsometry (IE) has been applied to generate laterally resolved thickness maps of spin-coated membranes in both the dry and fully hydrated state. Spin-coating offers a convenient preparation method for stacked supported membranes, and in-depth thickness maps for such films
Shubhadeep Banerjee et al.
International journal of pharmaceutics, 436(1-2), 786-797 (2012-08-14)
pH-responsive polymers render liposomes pH-sensitive and facilitate the intracellular release of encapsulated payload by fusing with endovascular membranes under mildly acidic conditions found inside cellular endosomes. The present study reports the use of high-molecular weight poly(styrene-co-maleic acid) (SMA), which exhibits
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