生物来源
semisynthetic
质量水平
检测方案
≥99%
形式
powder
官能团
phospholipid
脂质类型
phosphoglycerides
运输
ambient
储存温度
−20°C
SMILES字符串
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O
InChI
1S/C44H88NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h42H,6-41H2,1-5H3/t42-/m1/s1
InChI key
NRJAVPSFFCBXDT-HUESYALOSA-N
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一般描述
通过单一水合步骤形成负载有所选分子的无热原的，成分明确的脂质体。
应用
- Amantadine interactions with phase separated lipid membranes.: This study explores the interactions between amantadine and phase-separated lipid membranes, providing insights into the role of 1,2-Distearoyl-sn-glycero-3-phosphocholine in membrane structure and function (Kinnun et al., 2024).
- Design of charge converting lipid nanoparticles via a microfluidic coating technique.: This research designs lipid nanoparticles with charge-converting capabilities using 1,2-Distearoyl-sn-glycero-3-phosphocholine, enhancing drug delivery systems (Zöller et al., 2024).
- Investigation and Comparison of Active and Passive Encapsulation Methods for Loading Proteins into Liposomes.: The study compares methods for protein encapsulation into liposomes using 1,2-Distearoyl-sn-glycero-3-phosphocholine, advancing drug delivery technologies (Pisani et al., 2023).
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Shubhadeep Banerjee et al.
International journal of pharmaceutics, 436(1-2), 786-797 (2012-08-14)
pH-responsive polymers render liposomes pH-sensitive and facilitate the intracellular release of encapsulated payload by fusing with endovascular membranes under mildly acidic conditions found inside cellular endosomes. The present study reports the use of high-molecular weight poly(styrene-co-maleic acid) (SMA), which exhibits
Mette Marie Bruun Nielsen et al.
Langmuir : the ACS journal of surfaces and colloids, 29(5), 1525-1532 (2013-01-04)
Imaging ellipsometry (IE) has been applied to generate laterally resolved thickness maps of spin-coated membranes in both the dry and fully hydrated state. Spin-coating offers a convenient preparation method for stacked supported membranes, and in-depth thickness maps for such films
Hiroyuki Nakamura et al.
Organic & biomolecular chemistry, 10(7), 1374-1380 (2011-12-24)
The fluorescence-labeled closo-dodecaborane lipid (FL-SBL) was synthesized from (S)-(+)-1,2-isopropylideneglycerol as a chiral starting material. FL-SBL was readily accumulated into the PEGylated DSPC liposomes prepared from DSPC, CH, and DSPE-PEG-OMe by the post insertion protocol. The boron concentrations and the fluorescent
Xiaoming Xu et al.
International journal of pharmaceutics, 423(2), 410-418 (2011-12-31)
A mathematical model has been developed to predict the encapsulation efficiency of hydrophilic drugs in unilamellar liposomes, and will be useful in formulation development to rapidly achieve optimized formulations. This model can also be used to compare drug encapsulation efficiencies
Pan Li et al.
Journal of controlled release : official journal of the Controlled Release Society, 162(2), 349-354 (2012-07-18)
Ultrasound targeted microbubble destruction (UTMD) was one of the most promising strategies to enhance drug delivery in cancer therapy. Microbubbles (MBs) serve as a vehicle to carry anti-tumor drugs and locally release them when exposed to therapeutic ultrasound, resulting in
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