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Merck
CN

P1132

Sigma-Aldrich

Pterine

~95%

别名:

2-氨基-3-羟基蝶啶, 2-氨基-4-氧代二氢蝶啶

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About This Item

经验公式(希尔记法):
C6H5N5O
CAS号:
分子量:
163.14
Beilstein:
150294
EC 号:
MDL编号:
UNSPSC代码:
12352202
PubChem化学物质编号:
NACRES:
NA.77

生物来源

synthetic

质量水平

方案

~95%

表单

powder

储存温度

2-8°C

SMILES字符串

Nc1nc(O)c2nccnc2n1

InChI

1S/C6H5N5O/c7-6-10-4-3(5(12)11-6)8-1-2-9-4/h1-2H,(H3,7,9,10,11,12)

InChI key

HNXQXTQTPAJEJL-UHFFFAOYSA-N

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应用

蝶呤已用于:
  • 在光化学法中作为诱导DNA损伤
  • 在黄嘌呤氧化酶测定中作为底物
  • 作为标准品在薄层色谱法(TLC)中用于定量微生物中法蝶呤

生化/生理作用

蝶呤由吡嗪和嘧啶组成,在酮基和氨基上有取代基。蝶呤存在于包括蓝细菌在内的所有生物中。可作为氧化还原酶类的辅助因子,并作为叶酸合成的前体。蝴蝶翅膀上的蝶呤吸收光并引起非相干散射。蝶呤通过脱氧鸟苷的羟基化诱导DNA的改变。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Febuxostat, an inhibitor of xanthine oxidase, suppresses lipopolysaccharide-induced MCP-1 production via MAPK phosphatase-1-mediated inactivation of JNK
Nomura J, et al.
PLoS ONE, 8(9), e75527-e75527 (2013)
Colors and pterin pigmentation of pierid butterfly wings
Wijnen B, et al.
Journal of Insect Physiology, 53(12), 1206-1217 (2007)
Andrea Sariego-Jamardo et al.
Pediatric neurology, 53(5), 422-426 (2015-10-18)
The mechanisms of the ketogenic diet remain unclear, but several predictors of response have been proposed. We aimed is to study the relationship between the etiology of epilepsy, cerebrospinal fluid neurotransmitters, pterins, and amino acids, and response to a ketogenic
Pterin function in bacteria
Feirer N and Fuqua C
Pteridines, 18(1), 23-36 (2017)
C l'Hélias et al.
Mutation research, 128(2), 147-152 (1984-09-01)
The experiments described in this paper show that synthetic pteridines, especially biopterin and pterin, injected directly into Drosophila melanogaster induce recessive lethals. On the contrary, D-neopterin seems to have little effect. A mutagenic effect has previously been shown for an

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