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Merck
CN

P0928

Sigma-Aldrich

7-羟基吩噁嗪酮二戊醚

别名:

7-(戊氧基)-3H-吩噁嗪-3-酮

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About This Item

经验公式(希尔记法):
C17H17NO3
CAS号:
分子量:
283.32
Beilstein:
8394939
MDL编号:
UNSPSC代码:
12161501
PubChem化学物质编号:
NACRES:
NA.47

方案

≥98% (TLC)

质量水平

表单

powder

溶解性

acetonitrile: 0.95- 1.05 mg/mL, clear, orange

储存温度

2-8°C

SMILES字符串

CCCCCOc1ccc2N=C3C=CC(=O)C=C3Oc2c1

InChI

1S/C17H17NO3/c1-2-3-4-9-20-13-6-8-15-17(11-13)21-16-10-12(19)5-7-14(16)18-15/h5-8,10-11H,2-4,9H2,1H3

InChI key

ZPSOKQFFOYYPKC-UHFFFAOYSA-N

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相关类别

一般描述

Resorufin pentyl ether is an analog of resazurin. Resorufin is a redox probe which is colorless and non-fluorescent in its reduced state. On oxidation, it fluoresces red. Resorufin is used widely as an indicator in microbiological media. It can be used to differentiate between actively metabolizing cells and inactive or dead cells.

应用

Resorufin pentyl ether has been used as a substrate to study the effects of Kaempferia parviflora extract on mouse hepatic cytochrome P450 enzymes.

生化/生理作用

Fluorimetric substrate for cytochrome P450 linked enzymes, CYP2B and CYP2B4.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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E S Tzanakakis et al.
Cell motility and the cytoskeleton, 48(3), 175-189 (2001-02-27)
Cultured rat hepatocytes self-assemble into three-dimensional structures or spheroids that exhibit ultrastructural characteristics of native hepatic tissue and enhanced liver-specific functions. The spheroid formation process involves cell translocation and changes in cell shape, indicative of the reorganization of the cytoskeletal
Advances in Microbial Ecology null
A Pietersma et al.
Free radical research, 28(2), 137-150 (1998-06-30)
The present study was undertaken to investigate the hypothesis that multiple oxygen radical generating systems contribute to the tumor necrosis factor (TNF) alpha-stimulated transcriptional activation of the vascular cell adhesion molecule (VCAM)-1 in endothelial cells. Experimental evidence has implicated the
Microbial Biofilms null
Canan Sapmaz et al.
Drug and chemical toxicology, 43(1), 13-21 (2018-05-19)
Morin is a flavonoid which is present in many plants. Endosulfan and 7,12-dimethylbenz[a]anthracene (DMBA) are toxic chemicals that humans are exposed to in their daily lives. In this study, the protective role of morin was investigated in endosulfan and DMBA

商品

一期生物转化反应在药物上引入或暴露官能团,目的是增加化合物的极性。尽管一期药物代谢发生在大多数组织中,但代谢的主要和首过部位发生在肝循环期间。

Phase I biotransformation reactions increase drug compound polarity, mainly occurring in hepatic circulation.

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