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P0376

苯酚 β-D-葡萄糖醛酸钠盐

Name: 苯酚 β-<SC>D</SC>-葡萄糖醛酸 钠盐
Brand: SIGMA

β-glucuronidase substrate, chromogenic, ≥90% (TLC), powder

别名:

酚酞单-β-葡糖苷酸, 酚酞葡糖醛酸

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About This Item

线性分子式:

C₂₆H₂₁O₁₀Na

CAS号:

6820-54-8

分子量:

516.43

EC 号:

229-896-3

MDL编号:

MFCD00051200

UNSPSC代码:

12352204

PubChem化学物质编号:

329820033

NACRES:

NA.28

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P0501

酚酞β-D-葡萄糖苷酸

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G0251

β-葡萄糖醛酸酶来源于牛肝脏

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G7017

β-葡萄糖醛酸酶来源于罗曼蜗牛

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M9130

4-甲基伞形基β-D-葡糖苷酸水合物

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487500

p-硝基苯基-β-D-葡萄糖醛酸盐

Sigma-Aldrich

N1875

Naphthol AS-BI β-D-glucuronide

Sigma-Aldrich

S9626

硫酸脂酶来源于罗曼蜗牛

Millipore

49159

D- (+)-葡萄糖一水合物

Sigma-Aldrich

77636

酚酞β-D-葡萄糖苷酸

产品名称

苯酚 β-D-葡萄糖醛酸钠盐, β-glucuronidase substrate

质量水平

200

方案

≥90% (TLC)

表单

powder

溶解性

H₂O: soluble 5 mg/mL

储存温度

−20°C

SMILES字符串

[Na+].O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C([O-])=O)Oc2ccc(cc2)C3(OC(=O)c4ccccc34)c5ccc(O)cc5

InChI

1S/C26H22O10.Na/c27-15-9-5-13(6-10-15)26(18-4-2-1-3-17(18)24(33)36-26)14-7-11-16(12-8-14)34-25-21(30)19(28)20(29)22(35-25)23(31)32;/h1-12,19-22,25,27-30H,(H,31,32);/q;+1/p-1/t19-,20-,21+,22-,25+,26?;/m0./s1

InChI key

GBLJULUMBNYFAK-PDFLYTMFSA-M

生化/生理作用

酚酞β-D-葡萄糖醛酸钠盐是一种β葡萄糖醛酸酶。它由注射酚酞的兔的尿生物合成。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

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分析证书(COA)

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Chromogenic substrates II. Phenolphthalein glucuronic acid as substrate for the assay of glucuronidase activity

Talalay P, et al.

The Journal of Biological Chemistry, 166(2), 757-772 (1946)

[9] Preparation and assay of substrates for $\beta$-glucuronidase

Fishman WH

Test (1957)

Improvement in intestinal function and health by the peel fiber derived from Citrus sinensis L cv Liucheng

Chi-Fai Chau, Fuu Sheu, Ya-Ling Huang and Li-Hung Su

Journal of the Science of Food and Agriculture, 85, 1211-1216 (2005)

Assay of beta-glucuronidase in bile following ion-pair extraction of pigments and bile acids.

W E Kurtin et al.

Analytical biochemistry, 147(2), 511-516 (1985-06-01)

A method for improving the assay of beta-glucuronidase in hepatic and gallbladder bile is described. The method uses ion-pair extraction with N,N,N-triheptyl-1-heptanaminium bromide to remove pigments and bile acids. Conjugated bilirubin, unconjugated bilirubin, and taurine and glycine conjugates of deoxycholic

Evidence for multiple glucuronide transporters in rat liver microsomes.

Miklós Csala et al.

Biochemical pharmacology, 68(7), 1353-1362 (2004-09-04)

The transport of glucuronides across the endoplasmic reticulum membrane is an important step in the overall process of biotransformation, although the mechanism remains unclear and the participating transporters are unidentified. Using a rapid filtration assay in combination with liquid chromatography-mass

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苯酚 β-D-葡萄糖醛酸钠盐