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安全信息

P0048

Sigma-Aldrich

匹莫林

≥98% (HPLC)

别名:

2-氨基-5-苯基 4(5H)-噁唑酮, 苯异妥因

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About This Item

经验公式（希尔记法）:
C9H8N2O2
CAS号:
2152-34-3
分子量:
176.17
EC 号:
218-438-8
MDL编号:
MFCD00083197
UNSPSC代码:
12352200
PubChem化学物质编号:
329819998
NACRES:
NA.77

方案

≥98% (HPLC)

表单

solid

药品控制

USDEA Schedule IV; Home Office Schedule 4.2; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

溶解性

DMSO: 28 mg/mL

创始人

Boehringer Ingelheim

储存温度

2-8°C

SMILES字符串

NC1=NC(=O)C(O1)c2ccccc2

InChI

1S/C9H8N2O2/c10-9-11-8(12)7(13-9)6-4-2-1-3-5-6/h1-5,7H,(H2,10,11,12)

InChI key

NRNCYVBFPDDJNE-UHFFFAOYSA-N

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生化/生理作用

匹莫林为中枢神经兴奋剂。匹莫林用于治疗注意缺陷多动障碍 (ADHD)。匹莫林为第 IV 类精神药品，因其不会造成食欲下降或导致口干而比其他兴奋剂具有优势。

特点和优势

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H302 + H312 + H332

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges, type P3 (EN 143) respirator cartridges

法规信息

新产品

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分析证书(COA)

Lot/Batch Number
029K4630

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Mohsin Ali et al.
Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 5(6), 562-568 (2010-05-15)
A recent American Academy of Sleep Medicine publication identified a need for research regarding idiopathic hypersomnia. We describe various clinical and polysomnographic features of patients with idiopathic hypersomnia, with an emphasis on response to pharmacotherapy. A retrospective review of our
Amber M Muehlmann et al.
Behavioural brain research, 217(1), 148-154 (2010-10-27)
Self-injurious behavior (SIB) is a debilitating characteristic that is prevalent across a broad spectrum of neurodevelopmental disorders. In most of these disorders, some individuals exhibit SIB, whereas others do not. However, the neurobiological mechanisms that confer vulnerability are virtually unexplored.
Nina Oestreicher et al.
Pharmacoepidemiology and drug safety, 16(12), 1268-1272 (2007-11-28)
A recent report linked methylphenidate (MPH) use in children to cytologic abnormalities in plasma lymphocytes, a possible cancer biomarker. The purpose of this study was to investigate the association of MPH use and childhood cancer risk. Using automated pharmacy databases
Darragh P Devine
Methods in molecular biology (Clifton, N.J.), 829, 65-84 (2012-01-11)
Self-injurious behaviour is highly prevalent in neurodevelopmental disorders. Interestingly, it is not restricted to any individual diagnostic group. Rather, it is exhibited in various forms across patient groups with distinct genetic defects and classifications of disorders. This suggests that there
Christopher M Bloom et al.
Crisis, 33(2), 106-112 (2012-02-22)
Historically, the field of self-injury has distinguished between the behaviors exhibited among individuals with a developmental disability (self-injurious behaviors; SIB) and those present within a normative population (nonsuicidal self-injury; NSSI),which typically result as a response to perceived stress. More recently
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