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安全信息

P0048

Sigma-Aldrich

匹莫林

≥98% (HPLC)

别名:

2-氨基-5-苯基 4(5H)-噁唑酮, 苯异妥因

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About This Item

经验公式（希尔记法）:
C9H8N2O2
CAS号:
2152-34-3
分子量:
176.17
EC 号:
218-438-8
MDL编号:
MFCD00083197
UNSPSC代码:
12352200
PubChem化学物质编号:
329819998
NACRES:
NA.77

方案

≥98% (HPLC)

表单

solid

药品控制

USDEA Schedule IV; Home Office Schedule 4.2; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

溶解性

DMSO: 28 mg/mL

创始人

Boehringer Ingelheim

储存温度

2-8°C

SMILES字符串

NC1=NC(=O)C(O1)c2ccccc2

InChI

1S/C9H8N2O2/c10-9-11-8(12)7(13-9)6-4-2-1-3-5-6/h1-5,7H,(H2,10,11,12)

InChI key

NRNCYVBFPDDJNE-UHFFFAOYSA-N

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生化/生理作用

匹莫林为中枢神经兴奋剂。
匹莫林为中枢神经兴奋剂。匹莫林用于治疗注意缺陷多动障碍 (ADHD)。匹莫林为第 IV 类精神药品，因其不会造成食欲下降或导致口干而比其他兴奋剂具有优势。

特点和优势

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H302 + H312 + H332

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges, type P3 (EN 143) respirator cartridges

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
029K4630

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Steven C Marcus et al.
Journal of the American Academy of Child and Adolescent Psychiatry, 50(5), 480-489 (2011-04-26)
This analysis assessed whether stimulant adherence was associated with improvement in academic grade point average (GPA) among children diagnosed with and treated for attention-deficit/hyperactivity disorder (ADHD). Medicaid claims were merged with academic records from Philadelphia public schools of Medicaid-eligible children
Fatma A Etwel et al.
Drug safety, 31(2), 169-180 (2008-01-26)
Pemoline is a CNS stimulant that was introduced in 1975 in the US and was used to treat children with attention deficit hyperactivity disorder. Pemoline was withdrawn from the market 30 years later because of fatal hepatotoxicity associated with its
Amber M Muehlmann et al.
Behavioural brain research, 189(1), 32-40 (2008-02-05)
Self-injurious behaviour (SIB) is exhibited by individuals with a broad variety of developmental disorders and genetic abnormalities, including autism and Lesch-Nyhan, Prader-Willi and Rett syndromes. Most research has focused on environmental factors that reinforce SIB, and less is known about
Pharmacologic treatments for fatigue associated with palliative care.
Marilyn Kirshbaum
Clinical journal of oncology nursing, 15(4), 438-439 (2011-08-04)
Scott P Novak et al.
Substance abuse treatment, prevention, and policy, 2, 32-32 (2007-11-02)
Emerging evidence suggests that nonmedical use (NMU) of prescription attention deficit/hyperactivity disorder (ADHD) medications is rising, but many previous investigations have used clinical or regionally based samples or limited their investigations to stimulants rather than to medications specifically used to
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