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Merck
CN

O9765

Sigma-Aldrich

荭草苷

≥97% (HPLC)

别名:

8-β-D-Glucopyranosyl-3′,4′,5,7-四羟基黄酮, 荭草素, 荭草素 8-C-β-D-吡喃葡萄糖苷, 荭草苷

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About This Item

经验公式(希尔记法):
C21H20O11
CAS号:
分子量:
448.38
MDL编号:
UNSPSC代码:
12352205
PubChem化学物质编号:
NACRES:
NA.25

质量水平

方案

≥97% (HPLC)

表单

powder

颜色

yellow

溶解性

1 M NaOH: 1 mg/mL, clear, yellow-orange

应用

metabolomics
vitamins, nutraceuticals, and natural products

储存温度

2-8°C

SMILES字符串

OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)cc(O)c3C(=O)C=C(Oc23)c4ccc(O)c(O)c4

InChI

1S/C21H20O11/c22-6-14-17(28)18(29)19(30)21(32-14)16-11(26)4-10(25)15-12(27)5-13(31-20(15)16)7-1-2-8(23)9(24)3-7/h1-5,14,17-19,21-26,28-30H,6H2/t14-,17-,18+,19-,21+/m1/s1

InChI key

PLAPMLGJVGLZOV-VPRICQMDSA-N

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一般描述

荭草素(ORI)是一种木犀草素衍生物,也是水溶性8-C糖苷膳食黄酮。它的化学结构中有一个酮基、两个醚基和苯基。荭草素来源于多种药用植物,如O Ocimum sanctum(圣罗勒)、Phyllostachys类(竹叶)、Passiflora 类、Trollius类等。

应用

荭草素已被用于:
  • 作为抗炎症和抗增殖剂用于测试其对大鼠模型中1,2-二甲基肼(DMH)引起的结肠直肠癌的保护作用
  • 作为类黄酮用于研究其对抗霉素A引起的鼠C2C12骨骼肌细胞中线粒体功能障碍的保护作用
  • 作为流感病毒聚合酶PA亚单位的潜在核酸内切酶抑制剂

生化/生理作用

荭草素对于过氧化氢引起的SH-SY5Y神经母细胞具有神经保护作用。 它具有抗氧化、抗炎症、抗老化、抗抑郁剂、血管舒张和心脏保护作用。
黄酮苷存在于阿萨伊树、金梅草和西番莲中。抗病毒、抗菌和抗氧化剂。具有防辐射活性。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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